Comparison of baseline echocardiographic measures between patients with ≥ 15% decrease of GLS versus < 15% decrease at followup.
| N = 204 | < 15% Decrease GLS, n = 165 | ≥ 15% Decrease GLS, n = 39 | p |
|---|---|---|---|
| LVEDd mm, mean ± SD | 47 ± 5 | 47 ± 7 | 0.719 |
| LVEDV ml, mean ± SD | 81 ± 24 | 80 ± 24 | 0.795 |
| LVESV ml, mean ± SD | 31 ± 12 | 32 ± 13 | 0.667 |
| LVEF %, mean ± SD | 62 ± 7 | 60 ± 8 | 0.106 |
| Left atrial diameter mm, mean ± SD | 36 ± 6 | 35 ± 5 | 0.093 |
| E mm/s, mean ± SD | 77 ± 17 | 77 ± 21 | 0.114 |
| E/A ratio, mean ± SD | 1.16 ± 0.36 | 1.03 ± 0.32 | 0.008 |
| Lateral E′ cm/sec, mean ± SD | 11.49 ± 2.68 | 10.15 ± 2.49 | 0.005 |
| Lateral E′ ≤ 10 cm/s, n (%) | 45 (27) | 20 (51) | 0.005 |
| sPAP mmHg, mean ± SD | 25 ± 8 | 30 ± 8 | 0.004 |
| Elevated sPAP, n (%) | 10 (6) | 6 (15) | 0.036 |
| TAPSE mm, mean ± SD | 23 ± 4 | 22 ± 4 | 0.031 |
| Pericardial effusion, n (%) | 7 (4) | 1 (3) | 0.627 |
GLS: global longitudinal strain; LV: left ventricular; LVEDd: LV end-diastolic diameter; LVEDV: LV end-diastolic volume; LVESV: LV end-systolic volume; LVEF: LV ejection fraction; E/A: peak early (E) and late (A) diastolic velocities; sPAP: systolic pulmonary arterial pressure; TAPSE: tricuspid annular plane systolic excursion.