Baseline serology for SRC cases and SSc without SRC disease controls, when available. Data are %, n/N.
| Autoantibody | SRC, n = 31 | SSc without SRC, n = 322 | p |
|---|---|---|---|
| ANA | 83, 25/30 | 95, 228/242 | 0.04 |
| Speckled | 41, 9/22 | 33, 73/221 | NS |
| Nucleolar | 27, 6/22 | 41, 90/221 | NS |
| Homogeneous | 18, 4/22 | 16, 36/221 | NS |
| Centromere | 4, 1/22 | 9, 20/221 | NS |
| Other | 9, 2/22 | 1, 2/221 | NS |
| ARA | 50, 7/14 | 19, 15/76 | 0.02 |
| Centromere | 5, 1/17 | 52, 100/192 | < 0.001 |
| Scl-70 | 5, 1/17 | 18, 40/183 | NS |
| U3-RNP | 21, 3/14 | 28, 11/40 | NS |
| SSA | 35, 9/26 | 13, 29/228 | 0.006 |
| SSB | 8, 2/26 | 4, 9/219 | NS |
| C3/C4, % low | 5, 1/21 | 7, 10/138 | NS |
SRC: scleroderma renal crisis; SSc: systemic sclerosis; ANA: antinuclear antibodies; ARA: anti-RNA polymerase III antibodies; NS: not significant.