Baseline characteristics of the 2 groups in the study. Data are mean ± SD.
| Characteristics | Osteoporosis, n = 73 | Osteoarthritis, n = 45 | p |
|---|---|---|---|
| Age, yrs | 70.37 ± 6.5 | 68.60 ± 7.2 | 0.11 |
| Weight, kg | 59.41 ± 8.5 | 69.46 ± 12.7 | 0.02 |
| Height, cm | 161.97 ± 7.9 | 162.68 ± 8.3 | 0.75 |
| BMI, kg/m2 | 22.68 ± 3.1 | 26.14 ± 4.4 | 0.01 |
| Erythrocyte count, 1012/l | 4.27 ± 0.5 | 4.24 ± 0.6 | 0.88 |
| Leukocyte count, 109/l | 8.75 ± 3.1 | 6.49 ± 1.8 | 0.02 |
| Neutrophile granulocyte, 109/l | 6.96 ± 3.1 | 4.2 ± 2.0 | 0.001 |
| Lymphocyte, 109/l | 1.39 ± 0.5 | 1.81 ± 0.9 | 0.27 |
| Monocyte, 109/l | 0.57 ± 0.2 | 0.50 ± 0.1 | 0.68 |
| Albumin, g/l | 36.34 ± 4.3 | 38.12 ± 4.8 | 0.13 |
| Cholesterol, mmol/l | 4.73 ± 1.2 | 4.9 ± 1.2 | 0.59 |
| Triglyceride, mmol/l | 1.21 ± 1.1 | 1.14 ± 0.5 | 0.43 |
| Uric acid, µmol/l | 254.42 ± 86.3 | 363.36 ± 87.1 | 0.001 |
| Creatinine, µmol/l | 74.21 ± 27.4 | 77.24 ± 27.3 | 0.67 |
| ALP, u/l | 78.18 ± 25.5 | 74.36 ± 19.2 | 0.53 |
| Serum calcium, mmol/l | 2.18 ± 0.1 | 2.23 ± 0.1 | 0.11 |
| Serum phosphorus, mmol/l | 1.07 ± 0.2 | 1.16 ± 0.2 | 0.08 |
| Serum CTX, pg/ml | 571.54 ± 195.8 | 656.58 ± 175.3 | 0.37 |
| Serum BGP, ng/ml | 14.21 ± 7.7 | 21.01 ± 9.4 | 0.02 |
| Serum P1NP, ng/ml | 42.67 ± 18.8 | 69.55 ± 35.3 | 0.005 |
| Serum PTH, pg/ml | 39.21 ± 15.9 | 40.84 ± 13.8 | 0.73 |
| Serum 25(OH)D, ng/ml | 13.80 ± 7.6 | 18.03 ± 6.8 | 0.08 |
| BMD of L1–4, g/cm2 | 0.84 ± 0.3 | 0.91 ± 0.2 | 0.353 |
| BMD of FN, g/cm2 | 0.53 ± 0.13 | 0.76 ± 0.12 | 0.004 |
| BMD of total hip, g/cm2 | 0.62 ± 0.15 | 0.76 ± 0.13 | 0.009 |
Values in bold face are statistically significant. BMI: body mass index; ALP: alkaline phosphatase; CTX: collagen cross-linked C-telopeptide; BGP: bone Gla protein; P1NP: N-terminal propeptide of type-1 collagen; PTH: parathyroid hormone; 25(OH)D: 25-hydroxy vitamin D; BMD: bone mineral density; L1–4: lumbar spine 1–4; FN: femur neck.