Difference of EPC populations from bone marrow or peripheral blood between OP and OA groups. Data are mean ± SD.
| Osteoporosis, n = 73 | Osteoarthritis, n = 45 | p | |
|---|---|---|---|
| Bone marrow, ×106 ml | |||
| C | 0.51 ± 0.35 | 1.62 ± 1.0 | 0.004 |
| C1 | 0.34 ± 0.26 | 1.19 ± 0.69 | 0.036 |
| C2 | 0.03 ± 0.02 | 0.07 ± 0.04 | 0.027 |
| C3 | 0.12 ± 0.20 | 0.34 ± 0.31 | 0. 091 |
| C4 | 0.02 ± 0.03 | 0.02 ± 0.04 | 0.283 |
| C1% | 66.27 ± 21.2 | 76.13 ± 19.1 | 0.041 |
| C2% | 6.88 ± 3.1 | 3.81 ± 2.6 | 0.044 |
| C3% | 23.52 ± 23.7 | 18.39 ± 14.9 | 0.208 |
| C4% | 2.97 ± 4.7 | 1.89 ± 2.2 | 0.283 |
| Peripheral blood, ×104 ml | |||
| C | 0.53 ± 0.2 | 0.74 ± 0.3 | 0.93 |
| C1 | 0.33 ± 0.23 | 0.50 ± 0.33 | 0.30 |
| C2 | 0.09 ± 0.08 | 0.13 ± 0.10 | 0.52 |
| C3 | 0.09 ± 0.04 | 0.10 ± 0.08 | 0.71 |
| C4 | 0.02 ± 0.02 | 0.01 ± 0.03 | 0.15 |
| C1% | 61.94 ± 23.7 | 68.0 ± 23.7 | 0.30 |
| C2% | 11.30 ± 8.5 | 17.42 ± 13.3 | 0.52 |
| C3% | 17.05 ± 14.6 | 13.06 ± 9.4 | 0.71 |
| C4% | 3.96 ± 3.1 | 1.46 ± 1.3 | 0.15 |
Comparisons were assessed by the Mann-Whitney U test. P values < 0.05 were considered statistically significant and are in bold face. C = CD34+ cells; C1 = CD34+CD133–KDR+ cells; C2 = CD34+CD133+KDR+ cells; C3 = CD34+/CD133−/KDR− cells; C4 = CD34+/CD133+/KDR− cells; C1% = percentage of CD34+CD133−KDR+ cells from C; C2 = percentage of CD34+CD133+KDR+ cells from C; C3 = percentage of +/CD133−/KDR–cells from C; C4 = percentage of CD34+/CD133+/KDR− cells from C. EPC: endothelial progenitor cells; OP: osteoporosis; OA: osteoarthritis; KDR: vascular endothelial growth factor receptor-2.