Characteristics | Mean ± SD or n (%) |
---|---|
Age at time of HRCT, yrs | 50 ± 12 |
Sex, female | 216 (82) |
Body mass index, kg/m2 | 29 ± 6 |
Ethnicity, white | 192 (73) |
Smoker, current or former | 97 (37) |
Alcohol, current | 96 (46) |
Proton pump inhibitor use, current | 171 (65) |
SSc disease subtype | |
Diffuse cutaneous | 129 (49) |
Limited cutaneous | 131 (49) |
Sine scleroderma | 5 (2) |
Years between first non-Raynaud SSc symptom and HRCT date | 6 ± 11 |
SSc specific antibodies, positive | |
Antitopoisomerase I (Scl-70) | 78 (30) |
Anticentromere antibodies | 48 (18) |
Anti-RNA polymerase III | 59 (23) |
Modified Rodnan skin score | 13 ± 11 |
Radiographic ILD present | 188 (71) |
FVC % predicted | 76 ± 18 |
DLCO % predicted | 60 ± 20 |
SSc: systemic sclerosis; HRCT: high-resolution computed tomography; ILD: interstitial lung disease; FVC: forced vital capacity.