Treatment complications during biologic therapy, comparing self-identified indigenous to non-indigenous patients.
| Outcome | Indigenous Event Rate | Non-indigenous Event Rate | Adjusted IRR (95% CI) | p |
|---|---|---|---|---|
| All-cause hospitalization | 17.7 | 17.7 | 1.4 (1.1–1.8) | 0.01 |
| Serious infection | 3.4 | 1.4 | 4.0 (2.3–7.0) | < 0.001 |
| Cancer | ||||
| Any malignancy | 1.5 | 1.3 | 2.6 (1.1–5.7) | 0.02 |
| Lung | 0.2 | 0.1 | 1.9 (0.2 to 17.5) | 0.57 |
| Breast | 0.0 | 0.1 | NC | |
| Colorectal | 0.0 | 0.1 | NC | |
| Lymphoproliferative | 0.2 | 0.1 | 2.3 (0.3–20.5) | 0.45 |
| Cardiovascular | ||||
| Composite event rate | 4.2 | 20.0 | 0.8 (0.4–1.6) | 0.45 |
| Myocardial infarction | 0.8 | 0.7 | 3.5 (1.2–10.2) | 0.08 |
| Congestive heart failure | 1.5 | 10.0 | 0.6 (0.3–1.2) | 0.13 |
| Cerebrovascular accident | 1.9 | 9.4 | 0.6 (0.3–1.3) | 0.17 |
| Mortality | 0.0 | 0.7 | NC |
IRR: incidence rate ratio; NC: not calculable.