Clinical and laboratory characteristics of patients with systemic sclerosis (SSc) in Korea. Values are n (%) or mean ± SD.
| Characteristics | Patients with SSc, n = 751 |
|---|---|
| Female | 651 (86.7) |
| dcSSc/lcSSc | 264 (35.2)/487 (64.8) |
| Age at diagnosis, yrs | 48.9 ± 13.3 |
| Onset age of RP, yrs | 44.5 ± 14.6 |
| Onset age of scleroderma, yrs | 46.0 ± 14.2 |
| Observation period, yrs | 6.4 ± 5.6 |
| BMI, kg/m2 | 22.3 ± 13.3 |
| Residence in urban area | 584 (77.8) |
| mRSS | 8.4 ± 7.1 |
| GERD | 247 (32.9) |
| ILD | 396 (52.7) |
| Cardiovascular involvement | 84 (11.2) |
| PAH | 102 (13.6) |
| Isolated PAH, % | 13 (1.7) |
| Renal crisis | 19 (2.5) |
| Cancer | 46 (6.1) |
| Death | 57 (7.6) |
| Pulmonary function test | |
| FVC, % predicted | 78.4 ± 19.8 |
| FEV1, % predicted | 83.1 ± 20.9 |
| FEV1/FVC, % predicted | 107.2 ± 13.7 |
| DLCO, % predicted | 65.5 ± 21.8 |
| Systolic PAP, mmHg | 32.5 ± 16.6 |
| ANA | 715/740 (96.6) |
| Anti-Scl-70 antibody | 302/710 (42.5) |
| ACA | 175/686 (25.5) |
| ARA | 90/571 (15.8) |
dcSSc: diffuse cutaneous SSc; lcSSc: limited cutaneous SSc; RP: Raynaud phenomenon; BMI: body mass index; mRSS: modified Rodnan skin score; GERD: gastroesophageal reflux disease; ILD: interstitial lung disease; PAH: pulmonary arterial hypertension; FVC: forced vital capacity; FEV1: forced expiratory volume in 1 s; PAP: pulmonary arterial pressure; ANA: antinuclear antibody; ACA: anticentromere antibody; ARA: anti-RNA polymerase III.