Results of multivariate regression analysis for the prediction of SOST serum levels in all patient cohorts.
| Independent Variables | Regression Coefficient | 95% CI |
|---|---|---|
| Anti-SOST-IgG, IU/ml | −1.85 | −4.27 to −1.05 |
| Sex, male vs female | −13.1 | −34.76 to 70.45 |
| Age, yrs | −0.92 | −2.50 to 0.36 |
| Smoking habits, yes vs no | 19.44 | −49.37 to 75.68 |
| IBD duration, yrs | 1.81 | −0.83 to 3.78 |
| Articular symptom duration, mos | −0.40 | −1.23 to 0.09 |
| Corticosteroid therapy | 6.70 | −53.53 to 37.50 |
| DMARD therapy | −1.33 | −86.73 to 9.61 |
The patients analyzed were all patients affected by IBD, with or without articular inflammation. Statistical analysis was performed using quantile regression analysis. Values in bold face are statistically significant. SOST: sclerostin serum levels; anti-SOST-IgG: anti-SOST immunoglobulin G serum levels; IBD: inflammatory bowel disease; DMARD: disease-modifying antirheumatic drugs.