Incidence of serious and opportunistic infections within the concurrent and biologic-alone groups.
| Event Category Type | Concurrent, n = 102 | Biologic Alone, n = 206 | ||
|---|---|---|---|---|
| Event No./Total No. Patient-Yrs | Events per 100 Patient-Yrs (95% CI) | Event No./Total No. Patient-Yrs | Events per 100 Patient-Yrs (95% CI) | |
| Serious infection requiring hospitalization | ||||
| Pneumonia | 2/246 | 0.81 (0.10–2.94) | 2/509 | 0.39 (0.05–1.42) |
| Bronchitis | — | — | 1/509 | 0.20 (0.01–1.09) |
| Serious infection requiring ER visit and IV antibiotics | ||||
| Pneumonia | 1/246 | 0.41 (0.01–2.26) | 1/509 | 0.20 (0.01–1.09) |
| Opportunistic infection requiring hospitalization | ||||
| Pleural Mycobacterium avium complex | — | — | 1/509 | 0.20 (0.01–1.09) |
| Serious infections | 3/246 | 1.22 (0.25–3.56) | 4/509 | 0.79 (0.21–2.01) |
| Serious or opportunistic infections (total) | 3/246 | 1.22 (0.25–3.56) | 5/509 | 0.98 (0.32–2.29) |
ER: emergency room; IV: intravenous.