Characteristics | Systemic Sclerosis, n = 40 | Controls, n = 10 | p |
---|---|---|---|
Women, n (%) | 33 (82.5) | 7 (70) | 0.387 |
Age, mean (SD), yrs | 51 (11) | 46 (10) | 0.187 |
Height, mean (SD), cm | 167 (7) | 166 (7) | 0.582 |
Body mass, mean (SD), kg | 71.6 (17.9) | 67.0 (8.6) | 0.438 |
BMI, mean (SD), kg/m2 | 25.7 (5.7) | 24.4 (2.3) | 0.523 |
RP duration, mean (SD), yrs | 13.4 (12.0) | - | - |
SSc disease duration, mean (SD), yrs | 9.5 (8.9) | - | - |
mRSS, mean (SD), units | 6.1 (8.0) | - | - |
Vasculopathy history, n (%) | |||
Digital ulcers | 11 (28) | - | - |
SSc renal crisis | 4 (10) | - | - |
PAH | 6 (15) | - | - |
Antibody presence, n (%) | |||
Antinuclear antibody | 40 (100) | - | - |
Centromere | 1 (3) | - | - |
RNA polymerase III | 8 (20) | - | - |
Scl-70 | 7 (18) | - | - |
Fibrillin | 2 (5) | - | - |
Th/To | 1 (3) | - | - |
RNP | 5 (13) | - | - |
Medications, n (%) | |||
Calcium channel blockers | 33 (83) | - | - |
Endothelin receptor antagonists | 2 (5) | - | - |
Phosphodiesterase inhibitors | 11 (28) | - | - |
ACE inhibitors | 3 (8) | - | - |
Immunosuppression | 15 (38) | - | - |
BMI: body mass index; mRSS: modified Rodnan skin score; RP: Raynaud phenomenon; SSc: systemic sclerosis; PAH: pulmonary arterial hypertension; ACE: angiotensin-converting enzyme.