Infections | AAV, n | AAV, Person-yrs | Rate | Ref., n | Ref., Person-yrs | Rate | Rate Ratio | 95% CI | p |
---|---|---|---|---|---|---|---|---|---|
All severe infections | 86 | 740 | 116.2 | 118 | 4602 | 25.6 | 4.53 | 3.39–6.00 | < 0.001 |
All septicemias | 19 | 1039 | 18.2 | 29 | 4906 | 5.91 | 3.09 | 1.64–5.66 | 0.004 |
Nonspecific septicemia | 9 | 1088 | 8.27 | 9 | 4953 | 1.82 | 4.55 | 1.60–13.8 | 0.02 |
Gram-negative septicemia | 9 | 1064 | 8.46 | 12 | 4958 | 2.42 | 3.49 | 1.30–9.29 | 0.03 |
Staphylococcus aureus septicemia | 3 | 1095 | 2.74 | 4 | 4959 | 0.81 | 3.40 | 0.50–51.2 | 0.2 |
Acute URTI | 15 | 1043 | 14.3 | 8 | 4942 | 1.62 | 8.88 | 3.54–25.9 | 0.001 |
Influenza and pneumonia | 46 | 918 | 50.1 | 73 | 4763 | 15.3 | 3.27 | 2.21–4.76 | < 0.001 |
Clostridium difficile | 7 | 1080 | 6.48 | 6 | 4957 | 1.21 | 5.35 | 1.54–23.8 | 0.03 |
Nonspecific infection | 12 | 1031 | 11.6 | 22 | 4880 | 4.51 | 2.58 | 1.16–5.43 | 0.04 |
Skin infections | 8 | 1060 | 7.55 | 7 | 4961 | 1.41 | 5.35 | 1.69–19.8 | 0.02 |
ANCA: antineutrophil cytoplasmic antibody; AAV: ANCA-associated vasculitis; Ref.: reference; URTI: upper respiratory tract infection.