Univariate and multivariate associations between patient characteristics and low adherence (PDC < 20%; n = 1296).
| Variables | Univariate Associations | Mutually Adjusted Associations | |||
|---|---|---|---|---|---|
| Patients with Low Adherence, PDC < 20%, n = 784 | Patients with Non-low Adherence, PDC ≥ 20%, n = 512 | p | OR (95% CI) for Low Adherence, PDC < 20% | p | |
| Male, n (%) | 65 (8.3) | 53 (10.4) | 0.207 | 0.71 (0.48–1.05) | 0.085 |
| Age, yrs, median (IQR) | 48.1 (39.5–55.5) | 49.2 (40.5–57.0) | 0.157 | ||
| SES score, 1–20 scale, median (IQR) | 12 (9–15) | 13 (10–15) | 0.007 | ||
| SES quintile*, % (n) | |||||
| I | 22.7 (178) | 20.3 (104) | 0.111 | 1.0 (ref.) | |
| II | 20.2 (158) | 15.6 (80) | 1.15 (0.8–1.67) | 0.443 | |
| III | 19.1 (150) | 19.7 (101) | 0.85 (0.6–1.21) | 0.372 | |
| IV | 17.9 (140) | 20.1 (103) | 0.74 (0.52–1.06) | 0.104 | |
| V | 20.2 (158) | 24.2 (124) | 0.68 (0.48–0.96) | 0.028 | |
| Immigrated ≥ 1990 | 16.7 (131) | 19.5 (100) | 0.194 | 0.73 (0.54–0.99) | 0.041 |
| Source of first diagnosis, % (n) | |||||
| Primary care physician | 46 (361) | 48.4 (248) | 0.694 | ||
| Physician with relevant specialty | 53.1 (416) | 50.8 (260) | |||
| Hospital | 0.9 (7) | 0.8 (4) | |||
| Medical conditions diagnosed prior to FM, % (n) | |||||
| Total anxiety and/or depression | 34.3 (269) | 39.8 (204) | 0.043 | ||
| Neither | 65.7 (515) | 60.2 (308) | |||
| Anxiety only | 21.9 (172) | 27.5 (141) | 0.021 | ||
| Depression only | 18.0 (141) | 24.2 (124) | 0.007 | ||
| Both anxiety and depression, both vs none or either | 10.6 (83) | 17.6 (90) | < 0.001 | 0.55 (0.40–0.76) | < 0.001 |
| Fatigue | 44.6 (350) | 49 (251) | 0.122 | ||
| Migraine, yes vs no | 21 (165) | 29.9 (153) | < 0.001 | 0.62 (0.48–0.80) | < 0.001 |
| Osteoarthritis | 15.9 (125) | 15.6 (80) | 0.878 | ||
| Arthritis | 15.8 (124) | 14.8 (76) | 0.636 | ||
| Irritable bowel syndrome | 8.3 (65) | 10.4 (53) | 0.207 | ||
| LE | 0.4 (3) | 0.8 (4) | 0.339 | ||
| Restless leg syndrome | 1.1 (9) | 0.6 (3) | 0.383 | ||
↵* SES: socioeconomic status categories are quintiles of the entire study population. P for trend = 0.108. PDC: proportion of days covered; IQR: interquartile range; FM: fibromyalgia; SLE: systemic lupus erythematosus.