Table 2.

Biomarker levels differences at the time of biopsy among 37 responders and 50 nonresponders. Values are geometric means ± SE.

BiomarkerBiomarker Levels at the Time of Biopsy
NonrespondersRespondersp*
TGF-β3.74 ± 0.212.61 ± 0.22< 0.0001
Ceruloplasmin9.76 ± 0.298.58 ± 0.300.006
Transferrin2.12 ± 0.320.93 ± 0.340.012
AGP11.44 ± 0.3610.24 ± 0.380.023
VDBP6.65 ± 0.315.65 ± 0.320.027
Hepcidin6.88 ± 0.608.70 ± 0.620.037
LPGDS6.19 ± 0.315.30 ± 0.280.044
MCP-16.87 ± 0.216.28 ± 0.220.057
NGAL3.77 ± 0.223.20 ± 0.230.079
KIM-17.37 ± 0.227.10 ± 0.230.402
Osteopontin4.66 ± 0.324.30 ± 0.340.432
Hemopexin8.10 ± 0.257.82 ± 0.260.443
Cystatin-C4.35 ± 0.204.10 ± 0.260.451
Adiponectin10.65 ± 0.3610.27 ± 0.370.463
LFABP3.10 ± 0.263.09 ± 0.310.975
  • * P values are computed using mixed effect models. NGAL: neutrophil gelatinase associated lipocalin; KIM-1: kidney injury molecule 1; MCP-1: monocyte chemotactic protein 1; AGP: α-1-acid glycoprotein; TGF-β: transforming growth factor-β; LFABP: liver-type fatty acid-binding protein 1; VDBP: vitamin D binding protein; LPGDS: lipocalin-like prostaglandin D synthase.