Studies examining the association between body weight and patellar cartilage.
| Study | Definition of Outcome | OA/non-OA | Variables Adjusted For | Results (95% CI or p value) | Conclusion |
|---|---|---|---|---|---|
| Patellar cartilage defects | |||||
| Cross-sectional studies: association between body weight and patellar cartilage defects | |||||
| Gunardi, et al26 | Presence of patellar cartilage defects | Non-OA | Age, bone and cartilage volume | Increased odds of defects, OR 1.04 (1.02–1.06), p = 0.001 | Higher body weight was significantly associated with increased odds of patellar cartilage defects in women |
| Teichtahl, et al27 | Presence of patellar cartilage defects | Non-OA | Age, patellar cartilage volume | Men, increased odds of defects, OR 1.09 (95% CI 1.04–1.15), p = 0.001; women, increased odds of defects, OR 1.09 (95% CI 1.06–1.13), p < 0.0001 | Higher body weight was significantly associated with higher odds of patellar cartilage defects in men and women |
| Hanna, et al23 | Patellar cartilage defects | Non-OA | Age, bone volume | Increased odds of defects, OR 1.04 (95% CI 1.01–1.07), p = 0.006 | Higher body weight was significantly associated with higher odds of patellar cartilage defects in women |
| Longitudinal studies: association between change in weight over previous period and current patellar cartilage defects | |||||
| Gunardi, et al26 | Presence of patellar cartilage defects | Non-OA | Age, bone and cartilage volume, baseline weight | No increased odds of defects, OR 1.00 (0.96–1.05), p = 0.96 | No significant association between increase in body weight and patellar cartilage defects in women |
| Teichtahl, et al27 | Presence of patellar cartilage defects | Non-OA | Age, patellar cartilage volume | Women, OR 1.10 (95% CI 1.02–1.18), p = 0.01; men, OR 1.06 (95% CI 0.95–1.17), p = 0.31 | Increased body weight was significantly associated with higher odds of patellar cartilage defects among women only |
| Patellar cartilage volume | |||||
| Cross-sectional studies: association between body weight and patellar cartilage volume | |||||
| Gunardi, et al26 | Patellar cartilage volume | Non-OA | Age, patella bone volume | β coefficient: −3.21 (−7.93 to 1.5), p = 0.18 | No significant association between body weight and patellar cartilage volume in women |
| Teichtahl, et al27 | Patellar cartilage volume | Non-OA | Age, patella bone volume | Women, patellar cartilage volume, regression coefficient: −6.8 (95% CI −12.2 to −1.5), p = 0.01; men, patellar cartilage volume, regression coefficient: 6.5 (95% CI −3.9 to 16.9), p = 0.26 | Higher body weight was significantly associated with reduced cartilage volume among women only |
| Hanna, et al23 | Patellar cartilage volume | Non-OA | Age, bone volume | No increased odds of reduced patellar cartilage volume, OR −4.3 (95% CI −9.2 to 0.7), p = 0.09 | No significant association between body weight and patellar cartilage volume in women |
| Longitudinal studies: association between change in weight over previous period and patellar cartilage volume | |||||
| Gunardi, et al26 | Patellar cartilage volume | Non-OA | Age, bone volume, baseline weight | β coefficient: −10.4 (−20.0 to −0.78), p = 0.03 | Increased body weight significantly associated with reduced patellar cartilage volume in women |
| Teichtahl, et al27 | Patellar cartilage volume | Non-OA | Age | Men, current patellar cartilage volume, regression coefficient: −0.3 (95% CI −26.0 to 25.5), p = 0.98; women, current patellar cartilage volume, regression coefficient: 2.1 (95% CI −10.4 to 14.6), p = 0.74 | No significant relationship between body weight and cartilage volume |
| Longitudinal studies: association between baseline weight and change in patellar cartilage volume | |||||
| Teichtahl, et al35 | Annual change in patellar cartilage volume | Non-OA | Age, patella bone volume, participation in strenuous physical activity | Relationship with annual change in patellar cartilage volume, regression coefficient: women 1.0 (95% CI −0.01 to 2.0), p = 0.05; men 1.1 (95% CI −0.3 to 2.6), p = 0.13 | Higher body weight was not associated with loss of cartilage volume |
| Longitudinal studies: association between changes in weight and change in patellar cartilage volume | |||||
| Teichtahl, et al36 | Asymptomatic population | Sex, baseline age, BMI, time between measures, respective baseline measure | −0.9 (−2.7 to 0.9), p = 0.32 | Percentage weight change was not associated with change in patellar cartilage volumes | |
OA: osteoarthritis; BMI: body mass index.