#1 | Confirmed | African American | 11 | F | 108.7 | 35.5 | 1:160 | Positive | Aggregates of minor salivary glands with several foci of periductal primarily lymphocytic inflammation consistent with SS. | Positive Schirmer test |
#2 | Confirmed | African American | 13 | F | 108.9 | 76.7 | ≥ 1:1280 | Positive | Multiple sections show regional mucous gland lobules exhibiting multiple discrete foci of lymphocytes and plasma cells consistent with SS. | Normal Schirmer test |
#3 | Probable | African American | 15 | M | 109.6 | 68.5 | ≥ 1:1280 | Positive | Deferred given history of autism and need for general anesthesia. | Anti-RNP antibody–positive, 113.9 units* |
#4 | Confirmed | White | 11 | M | 158.3 | Negative | 1:160 | Positive | Multiple sections show regional mucous gland lobules exhibiting duct ectasia, acinar degeneration, stromal fibrosis, and an infiltrate of lymphocytes and plasma cells, and focus score > 0 foci/4 mm2. | Reduced salivary pooling. Salivary gland cysts visualized on ultrasound. |