Table 4.

Composite measure specific to PsA.

MeasureDomainsNo. ItemsReliabilityValidityConsiderations
PsARC89,90TJC, SJC, PGA, PtGA4Not assessedChi-square = 19.3–27.9Does not include enthesitis, dactylitis, or skin disease assessment
PsAJAI91,92TJC, CRP, PGA, pain, PtGA, HAQ6Not determinedNot assessedDoes not include enthesitis, dactylitis, or skin disease assessment
DAPSA93,94TJC, SJC, PtGA, pain, CRP5Not determinedThe instrument correlated highly with other measures, including the DAS, SDAI, and CDAI
CPDAI95Peripheral joints, skin, enthesitis, dactylitis, and spinal manifestations*5Not assessedThe CPDAI demonstrates significant correlation with PtGA (r = 0.777) and PGA (r = 0.809) assessments and discriminates well between effectively and ineffectively treated patientsMore sensitive than other instruments to detect change in domains beyond joints and patient’s global, particularly in domains such as enthesitis, dactylitis, and the skin, which are important multidimensional components of PsA
PASDASTJC, SJC, PGA, PtGA, SF36 PCS, enthesitis, dactylitis, CRP8Correlation with other measuresMore sensitive than other instruments to detect change in disease activity
GRACE indexSJC, TJC, VAS patient’s global, VAS skin, VAS joints, HAQ, PASI, PsAQoL8Correlation with other measuresAs sensitive as other instruments to detect change in disease activity
  • * For each domain, individual instruments were used to assess the extent of disease activity as well as the effect on patient function and health-related quality of life. PsA: psoriatic arthritis; PsARC: Psoriatic Arthritis Response Criteria; PsAJAI: Psoriatic Arthritis Joint Activity Index; DAPSA: Disease Activity in Psoriatic Arthritis; CPDAI: Composite Psoriatic Disease Activity Index; PASDAS: Psoriatic Arthritis Disease Activity Score; TJC: tender joint count; SJC: swollen joint count; PGA: physician’s global assessment; PtGA: patient’s global assessment; CRP: C-reactive protein; HAQ: Health Assessment Questionnaire; SF-36 PCS: Medical Outcomes Study Short Form-36 physical component summary; VAS: visual analog scale; PASI: Psoriasis Area and Severity Index; PsAQoL: Psoriatic Arthritis Quality of Life; DAS: Disease Activity Score; SDAI: Simple Disease Activity Index; CDAI: Clinical Disease Activity Index.