Characteristics of participants at baseline visit. Data are presented as n (%) unless otherwise specified.
| Characteristics | All, n = 295 | Dead, n = 43 | Alive, n = 252 | p |
|---|---|---|---|---|
| Age, yrs, mean (SD) | 59.1 (14.7) | 69.9 (12.3) | 57.2 (14.3) | < 0.0001 |
| Female sex | 87 (29.5) | 19 (44) | 68 (27.0) | 0.03 |
| Māori or Pacific ethnicity | 77 (26.1) | 16 (37) | 61 (24.2) | 0.09 |
| Disease duration, yrs, mean (SD) | 5.0 (3.0) | 5.8 (3.2) | 4.9 (3.0) | 0.06 |
| Flare frequency, preceding 3 mos, mean (SD) | 1.7 (2.8) | 2.3 (0.2) | 1.5 (2.6) | 0.1 |
| Smoker | 38 (12.9) | 4 (9) | 34 (13.5) | 0.62 |
| HTN | 132 (44.8) | 23 (53) | 109 (43.3) | 0.25 |
| Hypercholesterolemia | 139 (47.1) | 22 (51) | 117 (46.4) | 0.62 |
| Type 2 diabetes | 41 (13.9) | 14 (33) | 27 (10.7) | 0.001 |
| History of CVD | 115 (39.0) | 32 (74) | 83 (32.9) | < 0.0001 |
| Diuretic use | 70 (23.7) | 25 (58) | 45 (17.9) | < 0.0001 |
| Loop diuretics | 53 (18.0) | 24 (56) | 29 (11.5) | < 0.0001 |
| Allopurinol use | 184 (62.4) | 32 (74) | 152 (60.3) | 0.09 |
| Colchicine use | 103 (34.9) | 23 (53) | 80 (31.8) | 0.01 |
| BMI, kg/m2, mean (SD) | 31.2 (6.5) | 32.2 (8.2) | 31.0 (6.2) | 0.28 |
| Presence of subcutaneous tophus | 51 (17.3) | 19 (44) | 32 (12.7) | < 0.0001 |
| Serum urate, mmol/l, mean (SD) | 0.41 (0.12) | 0.41 (0.11) | 0.40 (0.10) | 0.25 |
| Serum creatinine, µmol/l, mean (SD) | 104.8 (65.1) | 133.6 (101.5) | 99.9 (55.4) | 0.002 |
HTN: hypertension; CVD: cardiovascular disease; BMI: body mass index.