Variables | SUA | Univariate | Multivariate* | ||
---|---|---|---|---|---|
HR (95% CI) | p | HR (95% CI) | p | ||
Overall | ≤ 4.0 | 0.844 (0.739–0.964) | 0.012 | 1.017 (0.872–1.187) | 0.827 |
4.1–6.0 | Reference | Reference | |||
6.1–8.0 | 0.985 (0.860–1.129) | 0.83 | 0.918 (0.783–1.076) | 0.289 | |
> 8.0 | 1.396 (1.008–1.934) | 0.034 | 1.292 (0.908–1.840) | 0.155 | |
Men** | ≤ 4.0 | 2.154 (1.795–2.584) | < 0.001 | 1.348 (1.102–1.649) | 0.004 |
4.1–6.0 | Reference | Reference | |||
6.1–8.0 | 0.813 (0.703–0.940) | 0.005 | 0.931 (0.789–1.099) | 0.397 | |
> 8.0 | 1.108 (0.794–1.546) | 0.546 | 1.256 (0.875–1.801) | 0.216 | |
Women** | ≤ 4.0 | 0.742 (0.605–0.909) | 0.004 | 0.863 (0.679–1.097) | 0.230 |
4.1–6.0 | Reference | Reference | |||
6.1–8.0 | 0.764 (0.418–1.399) | 0.384 | 0.627 (0.319–1.234) | 0.177 | |
> 8.0 | 2.104 (0.295–15.002) | 0.458 | 4.158 (0.570–30.309) | 0.160 |
↵* In multivariate analysis, we adjusted for age, body mass index, diabetes mellitus, hypertension, creatinine, albumin, hemoglobin, C-reactive protein, glucose, mean arterial pressure, high-density lipoprotein, low-density lipoprotein, triglycerides, smoking, alcohol consumption, and exercise.
↵** Sex showed a statistically significant interaction for the SUA level (p for interaction = 0.049). SUA: serum uric acid.