Effect of tocilizumab on intraocular inflammation in treatment-refractory chronic uveitis in juvenile idiopathic arthritis (n = 17). Sparing of systemic corticosteroids and/or immunosuppressives was defined according to Saurenmann, et al32. Values are n (%) unless otherwise specified.
| Variables | Values |
|---|---|
| Active uveitis at baseline, no. patients | 17 |
| Ocular quiescence at any time during followup | 10 (58.8) |
| Mean duration until quiescence, mos | 5.7 |
| Recurrences after achieving quiescence | 3 (30) |
| Sparing of systemic corticosteroids and/or immunosuppressives | |
| Good | 2 (11.8) |
| Moderate | 11 (64.7) |
| Poor | 4 (23.5) |
| Patients with new complications | 4 (23.5) |
| Cataract | 2 (11.8) |
| Band keratopathy | 1 (5.9) |
| Posterior synechia | 1 (5.9) |
| Ocular hypertension | 1 (5.9) |
| Glaucoma | 1 (5.9) |
| Improvement of preexisting macular edema | 5 (100) |
| Inactivity of arthritis | 6 (54.5) |