SLE Outcomes | Microparticle Subtype | Crude Spearman Correlation | Partial Spearman Correlation, 3 Partial Variables: LDL-C, BMI, and Antimalarial Drugs | ||||||
---|---|---|---|---|---|---|---|---|---|
n | r | 95% CI | p | n | r | 95% CI | p | ||
SLEDAI-2K | Total annexin V+ mpIC | 191 | 0.12 | −0.02 to 0.26 | 0.1026 | 179 | 0.15 | 0–0.29 | 0.0498 |
SLEDAI-2K | CD41− annexin V+ mpIC | 191 | 0.00 | −0.14 to 0.14 | 0.9808 | 179 | 0.03 | −0.12 to 0.17 | 0.7321 |
SLEDAI-2K | CD41+ annexin V+ mpIC | 191 | 0.16 | 0.02–0.30 | 0.0266 | 179 | 0.21 | 0.06–0.34 | 0.0058 |
SLEDAI-2K | CD41+ annexin V− mpIC | 191 | 0.23 | 0.09–0.36 | 0.0013 | 179 | 0.28 | 0.14–0.41 | 0.0002 |
SDI | Total annexin V+ mpIC | 191 | 0.13 | −0.01 to 0.27 | 0.0635 | 179 | 0.14 | −0.01 to 0.28 | 0.0625 |
SDI | CD41− annexin V+ mpIC | 191 | 0.16 | 0.02–0.30 | 0.0236 | 179 | 0.18 | 0.03–0.32 | 0.0181 |
SDI | CD41+ annexin V+ mpIC | 191 | 0.08 | −0.06 to 0.22 | 0.2596 | 179 | 0.08 | −0.07 to 0.22 | 0.3042 |
SDI | CD41+ annexin V− mpIC | 191 | −0.12 | −0.26 to 0.02 | 0.0891 | 179 | −0.14 | −0.28 to 0.01 | 0.0675 |
CIMT | Total annexin V+ mpIC | 113 | 0.21 | 0.03–0.38 | 0.0253 | 106 | 0.21 | 0.01–0.38 | 0.0364 |
CIMT | CD41– annexin V+ mpIC | 113 | 0.23 | 0.04–0.39 | 0.0156 | 106 | 0.21 | 0.02–0.39 | 0.0292 |
CIMT | CD41+ annexin V+ mpIC | 113 | 0.14 | −0.05 to 0.32 | 0.1370 | 106 | 0.12 | −0.08 to 0.31 | 0.2304 |
CIMT | CD41+ annexin V− mpIC | 113 | 0.03 | −0.15 to 0.22 | 0.7236 | 106 | 0.06 | −0.14 to 0.25 | 0.5739 |
CPA | Total annexin V+ mpIC | 113 | 0.01 | −0.18 to 0.19 | 0.9384 | 106 | −0.02 | −0.22 to 0.17 | 0.8032 |
CPA | CD41− annexin V+ mpIC | 113 | 0.04 | −0.14 to 0.23 | 0.6412 | 106 | 0.01 | −0.19 to 0.2 | 0.9410 |
CPA | CD41+ annexin V+ mpIC | 113 | −0.01 | −0.19 to 0.18 | 0.9191 | 106 | −0.05 | −0.24 to 0.14 | 0.6082 |
CPA | CD41+ annexin V− mpIC | 113 | −0.03 | −0.22 to 0.15 | 0.7326 | 106 | −0.07 | −0.26 to 0.12 | 0.4546 |
Significant data are in bold face. SLE: systemic lupus erythematosus; LDL-C: low-density lipoprotein cholesterol; BMI: body mass index; SLEDAI-2K: Systemic Lupus Erythematosus Disease Activity Index 2000; SDI: Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index; CIMT: carotid intima-media thickness; CPA: carotid plaque area; mpIC: microparticle-containing immune complexes.