DU Category | Change during Open-label Treprostinil, Mean (SD) | Change from End of Extension Study to Time B, Mean (SD) | Paired Student T Test, p |
---|---|---|---|
Active | −0.17 (0.65) | 0.7 (2.09) | 0.0509 |
Indeterminate | −0.43 (0.82) | 0.35 (0.84) | 0.0009 |
Total | −0.6 (1.04) | 1.05 (2.16) | 0.0027 |
DU: digital ulcers; Time B: > 6–12 months after treprostinil discontinuation.