Convergent validity. Nonparametric correlations between composite severity scores and outcome measures. Nonparametric correlations between each outcome and each composite measure with 95% bootstrap CI. Bonferroni p value < 0.0009.
| Measures | DSS Summed Score | DSS WSS | PGA | |||
|---|---|---|---|---|---|---|
| Kendall τ | p | Kendall τ | p | Kendall τ | p | |
| SF-36 PCS | −0.26 (−0.30 to −0.22) | < 0.0001 | −0.25 (−0.29 to −0.20) | < 0.0001 | −0.31 (−0.36 to −0.26) | < 0.0001 |
| SF-36 MCS | −0.07 (−0.12 to −0.02) | 0.005 | −0.05 (−0.10 to −0.01) | 0.023 | −0.07 (−0.12 to −0.02) | 0.004 |
| HAQ | 0.32 (0.28–0.36) | < 0.0001 | 0.32 (0.27–0.36) | < 0.0001 | 0.30 (0.26–0.34) | < 0.0001 |
| Patient-reported | ||||||
| Pain | 0.19 (0.13–0.23) | < 0.0001 | 0.18 (0.13–0.23) | < 0.0001 | 0.20 (0.16–0.25) | < 0.0001 |
| Raynaud phenomenon | 0.15 (0.10–0.21) | < 0.0001 | 0.12 (0.07–0.16) | < 0.0001 | 0.09 (0.04–0.14) | 0.001 |
| Finger ulcers | 0.29 (0.24–0.33) | < 0.0001 | 0.22 (0.17–0.27) | < 0.0001 | 0.15 (0.09–0.20) | < 0.0001 |
| GI problems | 0.16 (0.11–0.21) | < 0.0001 | 0.12 (0.07–0.17) | < 0.0001 | 0.10 (0.04–0.15) | < 0.005 |
| Breathing | 0.21 (0.16–0.26) | < 0.0001 | 0.16 (0.12–0.21) | < 0.0001 | 0.21 (0.16–0.27) | < 0.0001 |
| Disease severity | 0.28 (0.23–0.33) | < 0.0001 | 0.27 (0.22–0.31) | < 0.0001 | 0.30 (0.26–0.34) | < 0.0001 |
| Measures | Spearman ρ | p | Spearman ρ | p | Spearman ρ | p |
|---|---|---|---|---|---|---|
| SF-36 PCS | −0.37 (−0.43 to −0.31) | < 0.0001 | −0.37 (−0.43 to −0.31) | < 0.0001 | −0.43 (−0.49 to −0.37) | < 0.0001 |
| SF-36 MCS | −0.09 (−0.16 to −0.03) | 0.005 | −0.08 (−0.15 to −0.01) | 0.023 | −0.10 (−0.16 to −0.03) | 0.005 |
| HAQ | 0.43 (0.38–0.49) | < 0.0001 | 0.44 (0.38–0.49) | < 0.0001 | 0.40 (0.34–0.45) | < 0.0001 |
| Patient-reported | ||||||
| Pain | 0.25 (0.19–0.31) | < 0.0001 | 0.25 (0.18–0.31) | < 0.0001 | 0.27 (0.20–0.33) | < 0.0001 |
| Raynaud phenomenon | 0.20 (0.13–0.26) | < 0.0001 | 0.16 (0.10–0.23) | < 0.0001 | 0.11 (0.04–0.17) | < 0.0001 |
| Finger ulcers | 0.36 (0.30–0.42) | < 0.0001 | 0.29 (0.23–0.35) | < 0.0001 | 0.18 (0.12–0.25) | < 0.0001 |
| GI problems | 0.20 (0.13–0.27) | < 0.0001 | 0.17 (0.10–0.24) | < 0.0001 | 0.12 (0.06–0.18) | < 0.005 |
| Breathing | 0.27 (0.21–0.33) | < 0.0001 | 0.22 (0.15–0.28) | < 0.0001 | 0.27 (0.20–0.33) | < 0.0001 |
| Disease severity | 0.37 (0.31–0.43) | < 0.0001 | 0.37 (0.32–0.42) | < 0.0001 | 0.39 (0.34–0.45) | < 0.0001 |
DSS: Medsger Disease Severity Scale; WSS: weighted summed score; PGA: physician’s global assessment; SF-36: Medical Outcomes Study Short Form-36; PCS: physical component summary; MCS: mental component summary; HAQ: Health Assessment Questionnaire; GI: gastrointestinal.