Rate of selected comorbidities (per 1000 yrs of followup) among 95 women and 91 men with AAV compared with 380 and 364 age- and index year–matched reference persons from background population.
| Comorbidities | Rate Cases | Rate Reference Population | Rate Ratio | 95% CI | p |
|---|---|---|---|---|---|
| IHD* | |||||
| Men | 40.0 | 25.5 | 1.6 | 0.9–2.7 | 0.1 |
| Women | 23.5 | 15.7 | 1.5 | 0.7–2.8 | 0.2 |
| CVA* | |||||
| Men | 12.2 | 15.2 | 0.8 | 0.3–1.9 | 0.5 |
| Women | 14.2 | 9.5 | 1.5 | 0.6–3.5 | 0.3 |
| HTN | |||||
| Men | 117.4 | 79.5 | 1.5 | 1.0–2.1 | 0.05 |
| Women | 84.7 | 65.9 | 1.3 | 0.9–1.8 | 0.2 |
| DM | |||||
| Men | 41.5 | 27.0 | 1.5 | 0.8–2.7 | 0.1 |
| Women | 46.6 | 17.9 | 2.6 | 1.5–4.4 | 0.004 |
| Dyslipoproteinemias | |||||
| Men | 8.1 | 24.8 | 0.3 | 0.1–0.9 | 0.002 |
| Women | 14.0 | 14.1 | 1.0 | 0.4–2.2 | 0.9 |
| VTE* | |||||
| Men | 17.1 | 5.1 | 3.4 | 1.2–9.2 | 0.05 |
| Women | 14.3 | 2.7 | 5.3 | 1.7–19.5 | 0.02 |
| Thyroid disease | |||||
| Men | 8.1 | 4.7 | 1.7 | 0.4–6.2 | 0.4 |
| Women | 48.3 | 21.6 | 2.2 | 1.3–3.7 | 0.01 |
| Psychological disorders | |||||
| Men | 52.5 | 47.7 | 1.1 | 0.7–1.8 | 0.6 |
| Women | 70.9 | 70.6 | 1.0 | 0.7–1.5 | 0.9 |
| Osteoporosis | |||||
| Men | 30.6 | 3.4 | 9.0 | 3.5–26.7 | 0.001 |
| Women | 63.4 | 16.8 | 3.8 | 2.3–6.2 | < 0.001 |
| Fractures | |||||
| Men | 14.3 | 16.9 | 0.8 | 0.3–1.9 | 0.6 |
| Women | 27.1 | 22.4 | 1.2 | 0.6–2.2 | 0.5 |
↵* Only diagnoses assigned after hospitalization. AAV: antineutrophil cytoplasmic antibody–associated vasculitis; IHD: ischemic heart diseases; CVA: cerebrovascular accidents; HTN: hypertension; DM: diabetes mellitus; VTE: venous thromboembolism.