Characteristics of the 664 patients from the ESPOIR cohort at baseline and comparison of the remission group versus nonremission at 6 or 12 months according to the Boolean criteria. Student t test was performed for variables with a normal distribution and Mann-Whitney U test for variables with a non-normal distribution. Values are median (interquartile range) unless otherwise specified.
| Variables | Baseline, All Patients, n = 664 | Remission According to Boolean Criteria at 6 and/or 12 Mos | ||
|---|---|---|---|---|
| Remission, n = 165 | No Remission, n = 499 | p | ||
| Age, yrs, mean (SD) | 48.4 (12.3) | 44.9 (12.2) | 49.5 (12.1) | < 0.001 |
| Female, n (%) | 507 (76.4) | 158 (31.2) | 349 (68.9) | 0.09 |
| Erosive at baseline, n (%) | 220 (35) | 55 (35) | 165 (34.7) | 0.946 |
| Family history of RA, n (%) | 107 (16.1) | 21 (12.7) | 86 (17.2) | 0.172 |
| Disease duration, mos | 4.8 (2.9–7.1) | 4.2 (2.8–6.0) | 4.9 (2.9–7.3) | 0.06 |
| SJC, 0–28 | 6 (3–10) | 5 (2–9) | 6 (3–10) | 0.001 |
| TJC, 0–28 | 6 (3–13) | 5 (2–10) | 7 (4–14) | < 0.001 |
| PGA, 0–100, mean (SD) | 50.7 (22.1) | 43.6 (22.9) | 53.0 (21.4) | < 0.001 |
| PtGA, 0–100 | 64 (44–79) | 55.0 (31.0–75.0) | 66.0 (47–80) | < 0.001 |
| Function, 0–10 | 2.9 (1.2–4.6) | 2.5 (0.8–4.2) | 3.3 (1.7–5) | 0.005 |
| Pain, 0–10 | 4.5 (2.2) | 3.9 (2.2) | 4.8 (2.2) | < 0.001 |
| ESR, mm/h | 22 (12–38) | 19 (12–35) | 22 (12–39) | 0.55 |
| CRP, mg/l | 0.9 (0.5–2.5) | 0.9 (0.3–2) | 0.9 (0.5–2.5) | 0.247 |
| ACPA, n (%) | 266 (40) | 61 (37) | 205 (41) | 0.35 |
| RF+, n (%) | 290 (43.7) | 70 (42.4) | 220 (44.1) | 0.71 |
RA: rheumatoid arthritis; SJC: swollen joint count; TJC: tender joint count; PGA: physician’s global assessment; PtGA: patient’s global assessment; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; ACPA: anticitrullinated protein antibodies; RF: rheumatoid factor.