Table 2.

Univariate logistic regression models to estimate the associations among baseline variables that are potential predictors of remission by the Boolean criteria, DAS28, SDAI, CDAI, RAPID3, and RAPID3-SJ1 at 6 and/or 12 months.

Baseline
Variables
Boolean Criteria, n = 165 (24.8%)SDAI ≤ 3.3, n = 204 (30.8%)CDAI ≤ 2.8, n = 205 (30.9%)DAS28 ≤ 2.6, n = 339 (51.4%)RAPID3 ≤ 3, n = 273 (41.1%)RAPID3 ≤ 3 + SJ ≤ 1, n = 209 (31.5%)
OR (95% CI)pOR (95% CI)pOR (95% CI)pOR (95% CI)pOR (95% CI)pOR (95% CI)p
Age, yrs0.97 (0.96–0.98)< 0.0010.97 (0.95–0.98)< 0.0010.97 (0.95–0.98)< 0.0010.98 (0.97–0.99)0.020.98 (0.97–1.00)0.0110.97 (0.96–0.99)< 0.001
Disease duration, mos0.99 (0.96–1.01)0.260.99 (0.97–1.01)0.2550.99 (0.97–1.01)0.3000.99 (0.98–1.01)0.761.00 (0.98–1.02)0.9530.99 (0.98–1.01)0.91
Female1.05 (0.69–1.59)0.831.05 (0.71–1.56)0.7961.02 (0.69–1.51)0.9140.59 (0.41–0.85)0.050.83 (0.58–1.19)0.3120.94 (0.64–1.38)0.76
Erosive at baseline, yes = 11.01 (0.69–1.48)0.951.07 (0.75–1.52)0.7161.01 (0.71–1.44)0.9551.16 (0.83–1.61)0.380.91 (0.65–1.27)0.5870.85 (0.60–1.21)0.37
Family history of RA, yes = 10.70 (0.42–1.17)0.170.65 (0.40–1.06)0.0820.65 (0.40–1.05)0.0760.55 (0.36–0.85)0.0060.72 (0.47–1.11)0.1350.62 (0.38–1.00)0.05
TJC, 0–280.94 (0.91–0.97)< 0.0010.92 (0.89–0.95)< 0.0010.92 (0.89–0.94)< 0.0010.93 (0.91–0.95)< 0.0010.97 (0.94–0.99)0.0030.95 (0.92–0.97)< 0.001
SJC, 0–280.96 (0.92–0.99)0.010.94 (0.90–0.97)< 0.0010.93 (0.90–0.97)< 0.0010.98 (0.95–1.01)0.151.00 (0.97–1.03)0.9230.96 (0.93–0.99)0.01
PGA, 0–1000.98 (0.97–0.99)< 0.0010.98 (0.97–0.99)< 0.0010.98 (0.97–0.99)< 0.0010.98 (0.97–0.99)< 0.0010.98 (0.98–0.99)< 0.0010.98 (0.97–0.99)< 0.001
ESR0.99 (0.99–1.01)0.831.00 (0.99–1.01)0.8931.00 (1.00–1.01)0.6150.99 (0.98–0.99)0.031.00 (0.99–1.01)0.8091.00 (0.99–1.00)0.50
CRP0.99 (0.94–1.04)0.760.99 (0.94–1.04)0.6491.00 (0.96–1.05)0.8971.00 (0.96–1.05)0.891.00 (0.96–1.05)0.9081.01 (0.96–1.06)0.66
ACPA+, yes = 10.84 (0.58–1.21)0.350.84 (0.60–1.18)0.3160.88 (0.63–1.24)0.4670.82 (0.60–1.12)0.210.94 (0.69–1.29)0.7040.87 (0.62–1.22)0.42
RF+, yes = 11.07 (0.75–1.53)0.711.16 (0.83–1.62)0.3751.14 (0.82–1.60)0.4291.35 (0.99–1.84)0.061.09 (0.79–1.48)0.6071.13 (0.81–1.57)0.47
Function, 0–100.89 (0.82–0.97)0.0060.87 (0.81–0.94)< 0.0010.89 (0.82–0.96)0.0020.85 (0.80–0.91)< 0.0010.82 (0.77–0.89)< 0.0010.85 (0.79–0.92)< 0.001
Pain, 0–1000.98 (0.97–0.99)< 0.0010.98 (0.97–0.98)< 0.0010.98 (0.97–0.98)< 0.0010.98 (0.97–0.99)< 0.0010.97 (0.97–0.98)< 0.0010.98 (0.97–0.99)< 0.001
PtGA, 0–1000.99 (0.98–0.99)< 0.0010.99 (0.98–0.99)< 0.0010.99 (0.98–0.99)< 0.0010.98 (0.97–0.99)< 0.0010.98 (0.98–0.99)< 0.0010.99 (0.98–0.99)< 0.001
  • DAS28: Disease Activity Score at 28 joints; SDAI: Simplified Disease Activity Index; CDAI: Clinical Disease Activity Index; RAPID3: Routine Assessment of Patient Index Data 3; SJ: swollen joint; RA: rheumatoid arthritis; SJC: swollen joint count; TJC: tender joint count; PGA: physician’s global assessment; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; ACPA: anticitrullinated protein antibodies; RF: rheumatoid factor; PtGA: patient’s global assessment.