Baseline Variables | Boolean Criteria, n = 165 (24.8%) | SDAI ≤ 3.3, n = 204 (30.8%) | CDAI ≤ 2.8, n = 205 (30.9%) | DAS28 ≤ 2.6, n = 339 (51.4%) | RAPID3 ≤ 3, n = 273 (41.1%) | RAPID3 ≤ 3 + SJ ≤ 1, n = 209 (31.5%) | |||||||||
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OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | ||||
Age, yrs | 0.97 (0.96–0.98) | < 0.001 | 0.97 (0.95–0.98) | < 0.001 | 0.97 (0.95–0.98) | < 0.001 | 0.98 (0.97–0.99) | 0.02 | 0.98 (0.97–1.00) | 0.011 | 0.97 (0.96–0.99) | < 0.001 | |||
Disease duration, mos | 0.99 (0.96–1.01) | 0.26 | 0.99 (0.97–1.01) | 0.255 | 0.99 (0.97–1.01) | 0.300 | 0.99 (0.98–1.01) | 0.76 | 1.00 (0.98–1.02) | 0.953 | 0.99 (0.98–1.01) | 0.91 | |||
Female | 1.05 (0.69–1.59) | 0.83 | 1.05 (0.71–1.56) | 0.796 | 1.02 (0.69–1.51) | 0.914 | 0.59 (0.41–0.85) | 0.05 | 0.83 (0.58–1.19) | 0.312 | 0.94 (0.64–1.38) | 0.76 | |||
Erosive at baseline, yes = 1 | 1.01 (0.69–1.48) | 0.95 | 1.07 (0.75–1.52) | 0.716 | 1.01 (0.71–1.44) | 0.955 | 1.16 (0.83–1.61) | 0.38 | 0.91 (0.65–1.27) | 0.587 | 0.85 (0.60–1.21) | 0.37 | |||
Family history of RA, yes = 1 | 0.70 (0.42–1.17) | 0.17 | 0.65 (0.40–1.06) | 0.082 | 0.65 (0.40–1.05) | 0.076 | 0.55 (0.36–0.85) | 0.006 | 0.72 (0.47–1.11) | 0.135 | 0.62 (0.38–1.00) | 0.05 | |||
TJC, 0–28 | 0.94 (0.91–0.97) | < 0.001 | 0.92 (0.89–0.95) | < 0.001 | 0.92 (0.89–0.94) | < 0.001 | 0.93 (0.91–0.95) | < 0.001 | 0.97 (0.94–0.99) | 0.003 | 0.95 (0.92–0.97) | < 0.001 | |||
SJC, 0–28 | 0.96 (0.92–0.99) | 0.01 | 0.94 (0.90–0.97) | < 0.001 | 0.93 (0.90–0.97) | < 0.001 | 0.98 (0.95–1.01) | 0.15 | 1.00 (0.97–1.03) | 0.923 | 0.96 (0.93–0.99) | 0.01 | |||
PGA, 0–100 | 0.98 (0.97–0.99) | < 0.001 | 0.98 (0.97–0.99) | < 0.001 | 0.98 (0.97–0.99) | < 0.001 | 0.98 (0.97–0.99) | < 0.001 | 0.98 (0.98–0.99) | < 0.001 | 0.98 (0.97–0.99) | < 0.001 | |||
ESR | 0.99 (0.99–1.01) | 0.83 | 1.00 (0.99–1.01) | 0.893 | 1.00 (1.00–1.01) | 0.615 | 0.99 (0.98–0.99) | 0.03 | 1.00 (0.99–1.01) | 0.809 | 1.00 (0.99–1.00) | 0.50 | |||
CRP | 0.99 (0.94–1.04) | 0.76 | 0.99 (0.94–1.04) | 0.649 | 1.00 (0.96–1.05) | 0.897 | 1.00 (0.96–1.05) | 0.89 | 1.00 (0.96–1.05) | 0.908 | 1.01 (0.96–1.06) | 0.66 | |||
ACPA+, yes = 1 | 0.84 (0.58–1.21) | 0.35 | 0.84 (0.60–1.18) | 0.316 | 0.88 (0.63–1.24) | 0.467 | 0.82 (0.60–1.12) | 0.21 | 0.94 (0.69–1.29) | 0.704 | 0.87 (0.62–1.22) | 0.42 | |||
RF+, yes = 1 | 1.07 (0.75–1.53) | 0.71 | 1.16 (0.83–1.62) | 0.375 | 1.14 (0.82–1.60) | 0.429 | 1.35 (0.99–1.84) | 0.06 | 1.09 (0.79–1.48) | 0.607 | 1.13 (0.81–1.57) | 0.47 | |||
Function, 0–10 | 0.89 (0.82–0.97) | 0.006 | 0.87 (0.81–0.94) | < 0.001 | 0.89 (0.82–0.96) | 0.002 | 0.85 (0.80–0.91) | < 0.001 | 0.82 (0.77–0.89) | < 0.001 | 0.85 (0.79–0.92) | < 0.001 | |||
Pain, 0–100 | 0.98 (0.97–0.99) | < 0.001 | 0.98 (0.97–0.98) | < 0.001 | 0.98 (0.97–0.98) | < 0.001 | 0.98 (0.97–0.99) | < 0.001 | 0.97 (0.97–0.98) | < 0.001 | 0.98 (0.97–0.99) | < 0.001 | |||
PtGA, 0–100 | 0.99 (0.98–0.99) | < 0.001 | 0.99 (0.98–0.99) | < 0.001 | 0.99 (0.98–0.99) | < 0.001 | 0.98 (0.97–0.99) | < 0.001 | 0.98 (0.98–0.99) | < 0.001 | 0.99 (0.98–0.99) | < 0.001 |
DAS28: Disease Activity Score at 28 joints; SDAI: Simplified Disease Activity Index; CDAI: Clinical Disease Activity Index; RAPID3: Routine Assessment of Patient Index Data 3; SJ: swollen joint; RA: rheumatoid arthritis; SJC: swollen joint count; TJC: tender joint count; PGA: physician’s global assessment; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; ACPA: anticitrullinated protein antibodies; RF: rheumatoid factor; PtGA: patient’s global assessment.