Therapeutic interventions of severe thrombocytopenia among the 3 groups (CR, PR, and NR) in patients with SLE. Values are n (%) or mean ± SEM unless otherwise specified.
| Therapeutic Interventions | CR, n = 17 | PR, n = 8 | NR, n = 10 | p |
|---|---|---|---|---|
| Pulse MP | 8 (47.0) | 7 (87.5) | 5 (50.0) | 0.141 |
| Average daily steroid dose, mg/d | 80.9 ± 7.1 | 87.5 ± 8.1 | 104 ± 14.2 | 0.231 |
| IVIG | 6 (35.0) | 6 (75.0) | 7 (70.0) | 0.089 |
| HCQ | 7 (41.0) | 1 (12.5) | 5 (50.0) | 0.244 |
| TAC/CSA | 5 (29.0) | 5 (63.0) | 8 (80.0) | 0.031 |
| CTX | 11 (65.0) | 2 (25.0) | 7 (70.0) | 0.108 |
| RTX | 2 (12.0) | 4 (50.0) | 3 (30.0) | 0.117 |
| TPO | 0 (0.0) | 2 (25.0) | 3 (30.0) | 0.061 |
| Platelet pheresis transfusion | 4 (24.0) | 5 (63.0) | 9 (90.0) | 0.003 |
CR: complete response; PR: partial response; NR: no response; SEM: standard error of the mean; MP: methylprednisolone; IVIG: intravenous immunoglobulin; TAC: tacrolimus; CSA: cyclosporine; RTX: rituximab; TPO: thrombopoietin; CTX: cyclophosphamide.