APPENDIX 1.

Characteristics of patients with RA treated with MTX by response versus nonresponse to the survey, and those not treated with MTX by response versus nonresponse to the survey. Values are mean (SD) unless otherwise specified.

CharacteristicsTreated with MTX, Responded to SurveyTreated with MTX, Not Responded to SurveypNot Treated with MTX, Responded to SurveyNot Treated with MTX, Not Responded to Surveyp
n228284202270
Age, yrs53.18 (12.42)56.62 (12.43)0.00453.61 (12.51)55.02 (13.15)0.31
Female, n (%)184 (80.7)213 (76.6)0.26163 (80.7)225 (86.2)0.11
CDAI17.46 (14.72)16.59 (13.68)0.6717.28 (14.38)17.90 (13.75)0.52
mHAQ0.42 (0.47)0.43 (0.45)0.590.46 (0.48)0.48 (0.48)0.60
PGA, 0–10028.81 (24.08)25.99 (21.93)0.2727.45 (22.23)29.12 (23.08)0.43
PtGA, 0–10038.53 (26.87)40.36 (27.95)0.5240.52 (27.37)43.26 (27.14)0.32
Patient pain, 0–10039.15 (28.03)43.72 (29.67)0.1043.53 (30.07)46.32 (29.19)0.36
Disease duration, yrs7.31 (8.38)9.14 (8.82)0.00079.59 (8.44)10.04 (9.27)0.78
Glucocorticoid use, n (%)59 (25.9)76 (26.8)0.8256 (27.7)63 (23.3)0.27
Biologic use, n (%)214 (93.9)229 (80.6)< 0.0001167 (82.7)201 (74.4)0.03
  • RA: rheumatoid arthritis; MTX: methotrexate; CDAI: Clinical Disease Activity Index; mHAQ: modified Health Assessment Questionnaire; PGA: physician’s global assessment; PtGA: patient’s global assessment.