Variables associated to self-discontinuation in univariate and multivariate analysis.
| Variable | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| OR (95% CI) | p | OR (95% CI) | p | |
| Pain, VAS between 0 and 4 | 1.59 (0.99–2.56) | 0.054 | 2.00 (1.19–3.38) | 0.009 |
| No. biologics tried, more than 1 line | 1.80 (1.12–2.89) | 0.015 | 2.01 (1.20–3.36) | 0.008 |
| Person administering biologic, self-administration | 1.81 (1.05–3.12) | 0.032 | 1.82 (1.02–3.26) | 0.044 |
| Experienced side effects | 1.61 (0.92–2.80) | 0.096 | NS | NS |
| Use of alternative medicine | 1.65 (1.02–2.66) | 0.039 | NS | NS |
| Beliefs about treatments, score 1–12 | 1.40 (1.25–1.57) | < 0.001 | 1.43 (1.27–1.61) | < 0.001 |
| Medical and social support | 1.23 (1.07–1.42) | 0.003 | 1.17 (1.00–1.36) | 0.046 |
VAS: visual analog scale; NS: not significant.