Characteristics of the included studies for this metaanalysis.
| Studies | Identified Genes | Hardy-Weinberg Equilibrium | Country of Origin | Ethnicity of Participants | No. Patients with NPSLE | No. Patients with SLE | Method |
|---|---|---|---|---|---|---|---|
| Tsai, et al27 | IL1RN, IL1β -511, TNF-α -308 | Control yes, patients no | Taiwan | 100% Chinese | 35 | 87 | PCR |
| Tahmasebi, et al28 | IL1RN | Yes | Iran | 100% Iranian | 16 | 205 | PCR |
| Huang, et al29 | IL1β -511 | No | Taiwan | 100% Chinese | 9 | 52 | PCR |
| Santos, et al30 | IL6 -174 | Yes | Portugal | 100% white | 10 | 115 | PCR |
| Schotte, et al31 | IL6 -174 | Yes | Germany | 100% white | 62 | 211 | PCR |
| Hristova, et al32 | IL6 -174 | Yes | Bulgaria | 100% white | 10 | 52 | PCR |
| Asano, et al33 | IL6 -174 | Yes | Brazil | 85% African, 15% European | 54 | 80 | PCR |
| Rood, et al12 | IL-10 -1082 GA, -818 CT, -592 CA | Yes | Netherlands | 100% Dutch | 42 | 50 | PCR |
| Hirankarn, et al34 | IL-10 -1082 GA, -818 CT, -592 CA | Yes | Thai | 100% Thai | 10 | 230 | PCR |
| Toller-Kawahisa, et al35 | ITGAM (rs1143679) | Yes | Brazil | 100% Brazilian | 51 | 157 | PCR |
| Warchoł, et al36 | ITGAM (rs1143679) | Yes | Poland | 100% white | 32 | 154 | PCR |
| Monticielo, et al37 | MBL-2 | Yes | Brazil | 76.1% European, 23.9% African | 38 | 327 | PCR |
| Tsai, et al38 | MBL-2 | Yes | Taiwan | 100% Chinese | 32 | 150 | PCR |
| Piao, et al39 | MBL-2 | Yes | North America | 83.8% white, 16.2% other races | 21 | 130 | PCR |
| Garred, et al40 | MBL-2 | Yes | Denmark | 100% white | 4 | 91 | PCR |
| Garred, et al41 | MBL-2 | Yes | Denmark | 98% white | 9 | 99 | PCR |
| Sandrin-Garcia, et al42 | MBL-2, MBL-2 promoter | Yes | Brazil | 85% European, 15% African | 27 | 134 | PCR |
| Jakab, et al43 | MBL-2, MBL-2 promoter | Yes | Hungary | 100% white | 116 | 252 | PCR |
| Rood, et al44 | TNF-α -308 | Yes | Netherlands | 100% white | 43 | 99 | PCR |
| Lin, et al45 | TNF-α -308 | Yes | Taiwan | 100% Chinese | 17 | 161 | PCR |
| Santos, et al30 | TNF-α -308, LTA 252 | Yes | Portugal | 100% white | 10 | 115 | PCR |
| Ahmed, et al46 | TNF-α -308, LTA 252 | Yes | Egypt | 100% Egyptian | 16 | 100 | PCR |
| May, et al15 | TNF-α -308 | Yes | Australia | 99% white, 1% other | 17 | 64 | PCR |
| Angelo, et al47 | TNF-α -308 | Control yes, patients no | Brazil | 100% Brazilian | 26 | 98 | PCR |
| Dijstelbloem, et al48 | FcγRIIa | Yes | Netherlands | 100% white | 20 | 230 | PCR |
| Chen, et al49 | Fc γRIIa,FcγRIIIa, FcγRIIIb | No | Taiwan | 100% Chinese | 36 | 302 | PCR |
| Hong, et al50 | FcγRIIIa, FcγRIIIb | Yes | Korea | 100% Korean | 19 | 183 | PCR |
| Hatta, et al51 | FcγRIIa, FcγRIIIa, FcγRIIIb | Yes | Japan | 100% Japanese | 22 | 81 | PCR |
| Warchoł, et al52 | XRCC1 | Yes | Poland | 100% white | 53 | 265 | PCR |
| Lin, et al53 | XRCC1 | Yes | Taiwan | 100% Chinese | 14 | 164 | PCR |
| Huang, et al54 | Vitamin D receptor Fok I | Yes | Taiwan | 100% Chinese | 9 | 52 | PCR |
| Sakulpipatsin, et al55 | Vitamin D receptor BsmI | Yes | Thailand | 100% Thai | 18 | 101 | PCR |
| Luo, et al56 | Vitamin D receptor BsmI | Yes | China | 100% Chinese | 7 | 337 | PCR |
SLE: systemic lupus erythematosus; NPSLE: neuropsychiatric SLE; IL: interleukin; ITGAM: integrin alpha M; MBL: mannan-binding lectin; TNF-α: tumor necrosis factor-α.