Table 2.

Univariate relationships between clinical characteristics and lipoprotein subtypes.

Lipoprotein Subtypes	SLEDAI, Per 1 Unit Change		African American vs Not		Prednisone Per 5 mg/day Change		HCQ, Yes vs No		Renal Involvement, Yes vs No
Lipoprotein Subtypes	Mean Change	p	Mean Change	p	Mean Change	p	Mean Change	p	Mean Change	p
Total VLDL-P and chylomicrons	0.07	0.44	−7.6	0.12	3.1	< 0.0001	−10.4	0.018	−1.7	0.67
Large VLDL-P and chylomicrons	−0.003	0.93	−1.46	0.0077	0.09	0.11	−0.8	0.063	−0.003	0.99
Medium VLDL-P	0.10	0.52	−6.04	0.0023	0.47	0.037	−1.2	0.48	0.8	0.55
Small VLDL-P	−0.03	0.93	−0.04	0.99	2.66	< 0.0001	−8.97	0.013	−2.48	0.47
Total LDL-P	12.64	0.022	−148.3	0.076	37.39	< 0.0001	−92.00	0.16	112.14	0.022
IDL-P	−1.04	0.67	4.13	0.87	8.56	0.020	−0.12	0.61	−28.94	0.20
Large LDL-P	1.93	0.60	−39.16	0.51	19.97	0.0005	−31.25	0.47	42.22	0.19
Small LDL-P	12.43	0.0035	−113.5	0.087	9.80	0.15	−37.60	0.45	105.90	0.0049
Total HDL-P	−0.21	0.043	−7.38	0.0002	0.31	0.061	2.47	0.066	−0.33	0.72
Large HDL-P	−0.13	0.019	0.09	0.94	−0.09	0.26	1.68	0.015	−0.51	0.29
Medium HDL-P	−0.27	0.0057	−3.98	0.0010	−0.20	0.20	1.30	0.22	−1.57	0.071
Small HDL-P	0.11	0.29	−3.54	0.016	0.50	0.0025	0.11	0.93	1.35	0.16
VLDL size	−0.02	0.85	−4.13	0.0016	−0.16	0.36	0.21	0.86	0.65	0.52
LDL size	−0.02	0.14	0.12	0.47	0.02	0.50	−0.02	0.86	−0.17	0.10
HDL size	−0.01	0.40	0.37	0.0074	−0.02	0.13	0.26	0.0039	−0.026	0.68
TGC	−0.02	0.97	−24.66	0.0030	3.38	< 0.0001	−12.80	0.067	−0.15	0.98
VLDL and chylomicron TGC, total	−0.01	0.98	−21.23	0.0040	2.80	0.0005	−11.69	0.052	−0.09	0.98
HDL-C	−0.60	0.012	−6.74	0.19	0.08	0.82	6.03	0.045	−1.97	0.33
GlycA	4.15	0.0047	44.14	0.054	6.05	0.0089	−32.56	0.061	21.27	0.10

Significant data are in bold face. SLEDAI: Systemic Lupus Erythematosus Disease Activity Index; HCQ: hydroxychloroquine, VLDL: very low-density lipoprotein; VLDL-P: VLDL particle; LDL: low-density lipoprotein; LDL-P: LDL particle; IDL-P: intermediate-density lipoprotein particle; HDL: high-density lipoprotein; HDL-P: HDL particle; TGC: triglycerides; NMR: nuclear magnetic resonance; HDL-C: NMR-derived HDL cholesterol.