Variables | Status on Other Variables | General Population | RA | ||||
---|---|---|---|---|---|---|---|
First Yr | Subsequent Yr | ||||||
HR | 95% CI | HR | 95% CI | ||||
Calendar yr | 1994–1999 | Female, no somatic or psychiatric comorbidities | 1 | 5.4 | 4.2–6.8 | 2.4 | 2.1–2.8 |
2000–2005 | 1 | 5.1 | 4.3–6.3 | 2.3 | 2.0–2.5 | ||
2006–2011 | 1 | 4.8 | 4.0–5.8 | 1.9 | 1.7–2.2 | ||
Sex | Female | Yrs 2006–2011, no somatic or psychiatric comorbidities | 1 | 4.8 | 4.0–5.8 | 1.9 | 1.7–2.2 |
Male | 1 | 5.2 | 4.1–6.5 | 2.2 | 1.9–2.5 | ||
Somatic comorbidity | No | Female, yrs 2006–2011, no psychiatric comorbidities | 1 | 4.8 | 4.0–5.8 | 1.9 | 1.7–2.2 |
Yes | 1 | 3.6 | 3.0–4.3 | 1.6 | 1.4–1.7 | ||
Psychiatric comorbidity | No | Female, yrs 2006–2011, no somatic comorbidities | 1 | 4.8 | 4.0–5.8 | 1.9 | 1.7–2.2 |
Yes | 1 | 2.7 | 2.0–3.5 | 1.5 | 1.3–1.8 |
↵* The combined effect was calculated as the product of the relevant interaction and main effects (e.g., the HR in the first yr after diagnosis for patients with RA in 2006–2011 compared with the general population was calculated as the product of the HR for RA in 1994–1999 (= 5.4) and the RA × period interaction effect (= 0.9; Table 2). RA: rheumatoid arthritis.