Variables | First Yr | Subsequent Yrs | |||
---|---|---|---|---|---|
HR | 95% CI | HR | 95% CI | ||
Calendar yr | 1994–1999 | 1 | 1 | ||
2000–2005 | 1.6 | 1.3–2.0 | 1.9 | 1.6–2.2 | |
2006–2011 | 1.5 | 1.3–1.9 | 1.6 | 1.3–1.8 | |
Sex | Female | 1 | 1 | ||
Male | 0.7 | 0.6–0.9 | 0.8 | 0.8–0.9 | |
Somatic comorbidity | No | 1 | 1 | ||
Yes | 1.2 | 1.0–1.4 | 1.3 | 1.1–1.4 | |
Psychiatric comorbidity | No | 1 | 1 | ||
Yes | 1.2 | 1.0–1.5 | 1.5 | 1.3–1.7 | |
Highest education obtained | Elementary school/high school | 1 | 1 | ||
Vocational training | 1.0 | 0.9–1.0 | 0.9 | 0.9–1.0 | |
Tertiary/polytechnic school | 0.8 | 0.7–0.9 | 0.8 | 0.8–0.9 | |
Higher education, e.g., Master, PhD | 0.4 | 0.3–0.5 | 0.5 | 0.5–0.6 | |
NA | 1.2 | 1.0–1.6 | 1.0 | 0.9–1.1 | |
Physical job exposure, kg/day | 0 | 1 | 1 | ||
1–5999 | 1.6 | 1.5–1.8 | 1.3 | 1.3–1.4 | |
≥ 6000 | 1.9 | 1.7–2.1 | 1.5 | 1.5–1.6 |
↵* For risk factors where an interaction effect was found, the combined effect was calculated as the product of the interaction and the main effect (e.g., the HR in the first year after diagnosis for patients with RA in 2006–2011 compared with 1994–1999 was calculated as the product of the HR for 2006–2011 (= 1.7) and the RA × period interaction effect (= 0.9; Table 2). NA: not applicable.