Interobserver reliability [ICC (95% CI)] for 3 readers (readers 4, 5, and 6) naive to the HIMRISS method scoring BML and synovitis-effusion before and after calibration with the HIMRISS KT module v1 on STIR MRI scans from patients with hip OA obtained at baseline and 8 weeks after receiving intraarticular steroid.
| Exercise 1 (n = 16) | Exercise 2 (n = 23) | |||||
|---|---|---|---|---|---|---|
| Reader 4 | Reader 5 | Reader 6 | Reader 4 | Reader 5 | Reader 6 | |
| BL femoral BML | ||||||
| Reader 3* | 0.92 (0.84–0.96) | 0.85 (0.61–0.93) | 0.86 (0.74–0.93) | 0.90 (0.83–0.94) | 0.87 (0.76–0.93) | 0.85 (0.72–0.92) |
| Overall ICC# | 0.91 (0.85–0.95) | 0.89 (0.84–0.93) | ||||
| BL acetabular BML | ||||||
| Reader 3 | 0.91 (0.83–0.96) | 0.91 (0.83–0.96) | 0.83 (0.68–0.91) | 0.87 (0.77–0.92) | 0.84 (0.73–0.91) | 0.79 (0.66–0.88) |
| Overall ICC | 0.89 (0.82–0.94) | 0.83 (0.76–0.89) | ||||
| BL synovitis-effusion | ||||||
| Reader 3 | 0.52 (0.01–0.78) | 0.73 (0.51–0.86) | 0.63 (0.37–0.80) | 0.78 (0.56–0.88) | 0.76 (0.58–0.87) | 0.34 (−0.10–0.68) |
| Overall ICC | 0.62 (0.41–0.79) | 0.64 (0.42–0.79) | ||||
| Change femoral BML | ||||||
| Reader 3 | 0.32 (−0.04–0.60) | 0.76 (0.56–0.87) | 0.69 (0.45–0.83) | 0.69 (0.50–0.81) | 0.61 (0.40–0.77) | 0.34 (0.05–0.57) |
| Overall ICC | 0.62 (0.48–0.76) | 0.62 (0.50–0.73) | ||||
| Change acetabular BML | ||||||
| Reader 3 | 0.15 (−0.20–0.46) | −0.03 (−0.39–0.32) | 0.51 (0.20–0.73) | 0.28 (−0.02–0.52) | 0.22 (−0.07–0.48) | −0.06 (−0.35–0.24) |
| Overall ICC | 0.19 (0.08–0.38) | 0.29 (0.18–0.44) | ||||
| Change synovitis-effusion | ||||||
| Reader 3 | 0.27 (−0.10–0.56) | 0.22 (−0.13–0.52) | 0.11 (−0.24–0.44) | 0.63 (0.41–0.78) | 0.42 (0.16–0.63) | 0.20 (−0.20–0.46) |
| Overall ICC | 0.25 (0.12–0.43) | 0.35 (0.23–0.49) | ||||
↵* Reader 3 is a musculoskeletal radiologist and one of the original developers of the HIMRISS method.
↵# Overall ICC based on data from both HIMRISS naïve and expert readers. HIMRISS: Hip Inflammation Magnetic Resonance Imaging Scoring System; KT: knowledge transfer; BL: baseline; BML: bone marrow lesions; STIR: short-tau inversion recovery; MRI: magnetic resonance imaging; OA: osteoarthritis; ICC: intraclass correlation coefficient.