Characteristics | Monocentric Cohort | Register-derived Cohort | ||
---|---|---|---|---|
Patients | Controls* | Patients | Controls* | |
n | 159 | 1113 | 402 | 2814 |
Men, n (%) | 80 (50) | 560 (50) | 195 (48) | 1365 (48) |
Age at first hospitalization for GPA, yrs, median (IQR)** | 55 (43–63) | 55 (43–63) | 59 (46–68) | 59 (46–68) |
Followup, yrs, median (IQR)** | 5.7 (2.1–8.0) | 6.1 (2.9–8.0) | 4.6 (1.7–7.9) | 5.2 (2.6–8.0) |
Person-yrs of followup | 789 | 5880 | 1793 | 13.933 |
Deaths during followup, n | 28 | 104 | 85 | 345 |
Persons with at least 1 fracture during followup, n | 18 | 109 | 45 | 279 |
↵* Each patient was matched with 7 age- and sex-matched population controls.
↵** Followup began at date of first hospitalization for GPA (monocentric cohort)/date of first hospitalization for GPA at any Danish rheumatology department (register-derived cohort) and continued until first fracture, death, emigration, 8.0 years of followup, or December 31, 2010, whichever came first. GPA: granulomatosis with polyangiitis; IQR: interquartile range.