Characteristics | Patients with pSS | ||
---|---|---|---|
Premenopausal Patients | Menopausal Patients | Total Patients | |
n | 11 | 13 | 24 |
Mean age, yrs | 39.4 ± 7.35 | 59.8 ± 4.93 | 50.4 ± 12.00 |
Positive sialometry* | 3 (27.3) | 6 (46.2) | 9 (37.5) |
Swollen salivary glands** | 3 (27.3) | 1 (7.7) | 4 (16.6) |
ANA | 11 (100) | 13 (100) | 24 (100) |
Anti-SSA and/or anti-SSB | 10 (90.9) | 7 (53.8) | 17 (70.8) |
Positive minor salivary glands biopsy*** | 7 (100) | 4 (100) | 11 (100) |
ESSDAI | 2.1 ± 1.47 | 1.9 ± 2.06 | 2.0 ± 1.77 |
SSDDI | 1.4 ± 1.21 | 1.1 ± 1.19 | 1.21 ± 1.18 |
↵* Unstimulated sialometry-positive if less than 1.5 ml/15 min in 3 different determinations.
↵** Ever experienced swelling of any salivary gland.
↵*** Only 11 patients with pSS underwent a biopsy of minor salivary glands (7 menstruating patients and 4 menopausal patients). The biopsy was considered positive when the number of focus (50 cells/4 mm2) was ≥ 1. pSS: primary Sjögren syndrome; ANA: antinuclear antibodies; ESSDAI: EULAR Sjögren Syndrome Disease Activity Index; SSDDI: Sjögren Syndrome Disease Damage Index; EULAR: European League Against Rheumatism.