Table 1.

Rheumatological characteristics of patients with pSS (n = 24). Values are mean ± SD or n (%).

CharacteristicsPatients with pSS
Premenopausal PatientsMenopausal PatientsTotal Patients
n111324
Mean age, yrs39.4 ± 7.3559.8 ± 4.9350.4 ± 12.00
Positive sialometry*3 (27.3)6 (46.2)9 (37.5)
Swollen salivary glands**3 (27.3)1 (7.7)4 (16.6)
ANA11 (100)13 (100)24 (100)
Anti-SSA and/or anti-SSB10 (90.9)7 (53.8)17 (70.8)
Positive minor salivary glands biopsy***7 (100)4 (100)11 (100)
ESSDAI2.1 ± 1.471.9 ± 2.062.0 ± 1.77
SSDDI1.4 ± 1.211.1 ± 1.191.21 ± 1.18
  • * Unstimulated sialometry-positive if less than 1.5 ml/15 min in 3 different determinations.

  • ** Ever experienced swelling of any salivary gland.

  • *** Only 11 patients with pSS underwent a biopsy of minor salivary glands (7 menstruating patients and 4 menopausal patients). The biopsy was considered positive when the number of focus (50 cells/4 mm2) was ≥ 1. pSS: primary Sjögren syndrome; ANA: antinuclear antibodies; ESSDAI: EULAR Sjögren Syndrome Disease Activity Index; SSDDI: Sjögren Syndrome Disease Damage Index; EULAR: European League Against Rheumatism.