Chronic knee symptoms and history of injury predict a new knee injury within 12 months.
| Variables | Frequency of Injuries/total Observations, n (%) | Unadjusted OR for Injury (95% CI) | Adjusted* OR for Injury (95% CI) |
|---|---|---|---|
| Full OA initiative, 4435 participants, 875 injuries | |||
| No chronic ipsilateral knee symptoms | 422/21312 (2.0) | Reference | Reference |
| Chronic ipsilateral knee symptoms | 453/10118 (4.5) | 2.09 (1.82–2.40) | 1.84 (1.57–2.16) |
| No chronic contralateral knee symptoms | 502/21311 (2.4) | Reference | Reference |
| Chronic contralateral knee symptoms | 373/10119 (3.7) | 1.52 (1.32–1.75) | 1.02 (0.87–1.20) |
| No history of ipsilateral knee injury | 443/22275 (2.0) | Reference | Reference |
| History of ipsilateral knee injury | 432/9155 (4.7) | 2.09 (1.81–2.41) | 1.80 (1.56–2.09) |
| No history of contralateral knee injury | 518/22275 (2.3) | Reference | Reference |
| History of contralateral knee injury | 357/9155 (3.9) | 1.63 (1.41–1.89) | 1.43 (1.23–1.66) |
| Bilateral ROA, 1347 participants, 335 injuries | |||
| No chronic ipsilateral knee symptoms | 123/5324 (2.3) | Reference | Reference |
| Chronic ipsilateral knee symptoms | 212/4177 (5.1) | 2.00 (1.59–2.52) | 1.78 (1.37–2.30) |
| No chronic contralateral knee symptoms | 147/5323 (2.8) | Reference | Reference |
| Chronic contralateral knee symptoms | 188/4178 (4.5) | 1.56 (1.24–1.96) | 1.09 (0.85–1.41) |
| No history of ipsilateral knee injury | 153/6198 (2.5) | Reference | Reference |
| History of ipsilateral knee injury | 182/3303 (5.5) | 1.89 (1.49–2.39) | 1.65 (1.29–2.10) |
| No history of contralateral knee injury | 168/6198 (2.7) | Reference | Reference |
| History of contralateral knee injury | 167/3303 (5.1) | 1.82 (1.44–2.32) | 1.63 (1.28–2.09) |
| No ROA at all visits, 1204 participants, 153 injuries | |||
| No chronic ipsilateral knee symptoms | 100/7460 (1.3) | Reference | Reference |
| Chronic ipsilateral knee symptoms | 53/2091 (2.5) | 1.77 (1.25–2.50) | 1.62 (1.07–2.45) |
| No chronic contralateral knee symptoms | 110/7461 (1.5) | Reference | Reference |
| Chronic contralateral knee symptoms | 43/2090 (2.1) | 1.37 (0.95–1.97) | 1.01 (0.66–1.56) |
| No history of ipsilateral knee injury | 90/7333 (1.2) | Reference | Reference |
| History of ipsilateral knee injury | 63/2218 (2.8) | 2.11 (1.50–2.97) | 2.00 (1.39–2.86) |
| No history of contralateral knee injury | 107/7333 (1.5) | Reference | Reference |
| History of contralateral knee injury | 46/2218 (2.1) | 1.39 (0.95–2.02) | 1.19 (0.81–1.75) |
↵* In addition to the variables indicated, each model was adjusted for sex, age, and body mass index at each visit. Significant OR are in bold face. OA: osteoarthritis; ROA: radiographic osteoarthritis.