Radiographic changes from baseline to 5-year followup in the marginal, mild, and moderate pain trajectories. Values are mean (SD) unless otherwise specified.
| Variables | All Subjects | Marginal Pain | Mild Pain | Moderate Pain |
|---|---|---|---|---|
| n | 705 | 222 | 294 | 189 |
| KL change, % (n) | ||||
| Δ0 | 50 (306) | 56 (111) | 48 (120) | 48 (77) |
| Δ1 | 40 (239) | 37 (75) | 42 (107) | 38 (62) |
| Δ2 + Δ3 | 10 (60) | 7 (14) | 10 (26) | 14 (22) |
| Osteophyte area change, mm2 | 3.9 (7.8) | 0.3 (6.6) | 1.0 (7.7) | 1.7 (9.1) |
| Min JSW change, mm | 0.6 (1.1) | 0.4 (1.1) | 0.3 (1.1) | 0.3 (1.2) |
KL change: radiographic change from baseline to 5-year followup in index knee. Osteophyte area change: osteophyte change from baseline to 5-year followup in index knee. Min JSW change: change in minimal JSW from baseline to 5-year followup in index knee. KL: Kellgren-Lawrence grading scale; JSW: joint space width.