Characteristics of patients with pSS and control subjects. Values are n (%) unless otherwise specified.
| Characteristics | pSS, n = 2686 | Control, n = 10,744 | p |
|---|---|---|---|
| Age, yrs, median (IQR) | 45.31 (32.99–57.98) | 45.26 (32.93–57.99) | 0.996 |
| Age distribution | |||
| 20–39 | 1068 (39.8) | 4272 (39.8) | 0.946 |
| 40–59 | 1030 (38.3) | 4120 (38.3) | |
| ≥ 60 | 588 (21.9) | 2352 (21.9) | |
| Sex | |||
| Male | 760 (28.3) | 3040 (28.3) | > 0.999 |
| Female | 1926 (71.7) | 7704 (71.7) | |
| Income | |||
| Low | 1098 (40.9) | 5194 (48.3) | < 0.001* |
| Medium | 1050 (39.1) | 4175 (38.9) | |
| High | 538 (20.0) | 1375 (12.8) | |
| Degree of urbanization | |||
| Urban | 1695 (63.1) | 6729 (62.6) | 0.170 |
| Suburban | 754 (28.1) | 3152 (29.3) | |
| Rural | 199 (7.4) | 863 (8.0) | |
| Comorbidities | |||
| Hypertension | 517 (19.2) | 1916 (17.8) | 0.092 |
| Diabetes mellitus | 348 (13.0) | 1138 (10.6) | 0.001* |
| Dyslipidemia | 499 (18.6) | 1341 (12.5) | < 0.001* |
| Coronary artery disease | 22 (0.8) | 71 (0.7) | 0.367 |
| Congestive heart failure | 66 (2.2) | 202 (1.9) | 0.241 |
| Chronic pulmonary disease | 431 (16.0) | 1031 (9.6) | 0.001* |
| Malignancy | 58 (2.2) | 193 (1.8) | 0.231 |
| Followup, yrs, median (IQR) | 4.70 (2.93–7.17) | 4.70 (2.93–0.17) | 0.866 |
| Newly diagnosed psychiatric disorders | 215 (8.00) | 475 (4.4) | < 0.001* |
| Schizophrenia | 2 (0.1) | 24 (0.2) | 0.143 |
| Bipolar disorder | 6 (0.2) | 15 (0.1) | 0.409 |
| Depressive disorder | 85 (3.2) | 174 (1.6) | < 0.001* |
| Anxiety disorder | 67 (2.5) | 145 (1.3) | < 0.001* |
| Sleep disorder | 55 (2.0) | 117 (1.1) | < 0.001* |
↵* Statistical significance. pSS: primary Sjögren syndrome; IQR: interquartile range.