Variables | Mild Pain vs Marginal Pain | Moderate Pain vs Marginal Pain | ||||
---|---|---|---|---|---|---|
OR Univariate | OR Multivariate KL Model B | OR Multivariate OP Model C | OR Univariate | OR Multivariate KL Model B | OR Multivariate OP Model C | |
KL change | ||||||
Δ0 | Referent | Referent | Referent | Referent | Referent | |
Δ1 | 1.3 (0.9–2.0) | 1.4 (0.8–2.0) | 1.2 (0.8–1.9) | 1.1 (0.6–1.9) | 1.1 (0.6–1.9) | |
Δ2 + Δ3 | 1.7 (0.9–3.5)* | 2.0 (0.9–4.5)* | 2.3 (1.1–4.7)** | 2.9 (1.2–7.1)** | 2.8 (1.0–7.4)** | |
Osteophyte area change | 1.0 (1.0–1.0) | 1.0 (1.0–1.1) | 1.0 (1.0–1.1) * | 1.0 (1.0–1.1)* | ||
Min JSW change | 0.9 (0.8–1.1) | 0.9 (0.8–1.1) | ||||
Hosmer-Lemeshow goodness-of-fit test | 0.322 | 0.327 | 0.322 | 0.327 | ||
Pseudo Nagelkerke R2 | 0.226 | 0.228 | 0.226 | 0.228 |
↵* p value ≤ 0.1, cutoff point in univariate regression.
↵** p value ≤ 0.05. KL change: radiographic change from baseline to followup in index knee. OP area change: OP change from baseline to 5-year followup in index knee. Min JSW change: change in minimal JSW from baseline to followup in index knee. Multivariate KL model B: model corrected for baseline variables (BMI, education, hip pain, worrying, resting, comorbidity, OP size, KL grade) and KL change. Multivariate OP model C: model corrected for baseline variables (BMI, education, hip pain, worrying, resting, comorbidity, OP size) and KL change, change of OP size. KL: Kellgren-Lawrence grading scale; OP: osteophyte; JSW: joint space width; BMI: body mass index.