Baseline characteristics and their associations with leptin concentrations in patients with rheumatoid arthritis who have a large traditional cardiovascular disease risk burden.
| Characteristic | Association with Leptin Concentrations* | ||
|---|---|---|---|
| Partial R | p | ||
| AIMS depression score ≥ 4 | 32.1 | −0.284 | 0.05 |
| Antidepressants | 32.1 | −0.178 | 0.2 |
| Glucocorticoids | 1.9 | −0.147 | 0.3 |
| Antihypertensives | 73.6 | −0.024 | 0.9 |
| Lipid-lowering agents† | 35.8 | 0.073 | 0.6 |
| Insulin sensitivity–altering drugs‡ | 28.3 | 0.332 | 0.02 |
| Hormone replacement therapy§ | 9.4 | 0.039 | 0.8 |
| Vitamin D supplementation | 7.5 | 0.028 | 0.9 |
↵* Associations were assessed in mixed regression models adjusted for age, sex, and race2,3.
↵† Includes statin or/and ezetimibe.
↵‡ Comprises oral glucose lowering agents or/and insulin therapy.
↵§ Estrogen with or without progesterone used for menopausal symptoms. AIMS: Arthritis Impact Measure Scales.