Comparison of bone involvement assessed by aBMD and TBS in SSc, RA, and controls. Values are n (%) or mean ± SD unless otherwise specified.
| Characteristics | SSc, n = 65 | RA, n = 138 | Controls, n = 227 | SSc vs RA, p | SSc vs Controls, p | RA vs Controls, p |
|---|---|---|---|---|---|---|
| Lumbar spine TBS | 1.207 ± 0.145 | 1.247 ± 0.136 | 1.294 ± 0.121 | 0.128 | < 0.0001 | 0.0009 |
| Lumbar spine aBMD, g/cm2 | 1.007 ± 0.179 | 1.001 ± 0.202 | 1.060 ± 0.170 | 0.761 | 0.022 | 0.002 |
| Femoral neck aBMD, g/cm2 | 0.784 ± 0.142 | 0.768 ± 0.133 | 0.842 ± 0.127 | 0.500 | 0.0005 | < 0.0001 |
| Total hip aBMD, g/cm2 | 0.844 ± 0.137 | 0.814 ± 0.140 | 0.902 ± 0.136 | 0.168 | 0.003 | < 0.0001 |
| Fracture rate | 19/65 (29.0) | 46/138 (33.3) | 24/227 (10.6) | 0.682 | 0.0004 | < 0.0001 |
| Peripheral fractures | 13/65 (20.0) | 33/138 (23.9) | 23/227 (10.1) | 0.649 | 0.051 | 0.0007 |
| Vertebral fractures | 10/65 (15.4) | 20/138 (14.5) | 2/227 (0.09) | 0.980 | < 0.0001 | < 0.0001 |
| T score ≤ −2.5 SD at 1 site or more | 27/65 (41.5) | 59/138 (42.7) | 39/227 (17.1) | 0.993 | 0.0001 | < 0.0001 |
Significant data are in bold face. aBMD: areal bone mineral density; TBS: trabecular bone score; SSc: systemic sclerosis; RA: rheumatoid arthritis.