Multivariable regression models for new erosive disease or remission at followup. Model for multiple logistic regression included the following variables with p < 0.1: baseline antibody group for erosions at 12 months; baseline age, DAS28, HAQ, SJC, CRP for DAS28 remission at 12 months; baseline DAS28 for erosions at 24 months; baseline age, HAQ for DAS28 at 24 months.
| Characteristics | ACPA–RF– | n | ACPA+RF–* | n | ACPA–RF+* | n | ACPA+RF+* | n |
|---|---|---|---|---|---|---|---|---|
| 12 mos | ||||||||
| Erosions | 1 | 43 | 5.53 (1.44–21.20) | 34 | 1.46 (0.38–5.50) | 57 | 3.67 (1.13–12.08) | 99 |
| Remission | 1 | 121 | 0.84 (0.36–1.94) | 64 | 1.04 (0.51–2.12) | 102 | 0.76 (0.40–1.44) | 236 |
| 24 mos | ||||||||
| Erosions | 1 | 37 | 1.21 (0.29–5.05) | 25 | 1.40 (0.44–4.47) | 45 | 1.85 (0.65–5.24) | 85 |
| Remission | 1 | 87 | 0.68 (0.27–1.70) | 47 | 0.83 (0.38–1.80) | 79 | 0.95 (0.49–1.70) | 179 |
↵* Values are OR (95% CI). DAS28: 28-joint Disease Activity Score; HAQ: Health Assessment Questionnaire; SJC: swollen joint count of 28 joints; CRP: C-reactive protein; ACPA: anticitrullinated protein antibodies; RF: rheumatoid factor.