Table 1.

ACR definitions of clinical inactive disease and clinical remission for JIA. From: Wallace, et al. Arthritis Care Res 2011;63:929–363; with permission.

Definition of “clinical inactive disease (CID)” for JIA (all 6 conditions must be met)

  • No joints with active arthritis

  • No fever, rash, serositis, splenomegaly, or generalized lymphadenopathy attributed to JIA

  • No active uveitis

  • ESR or CRP level (or both if tested) within normal limits for the laboratory where tested, or, if elevated, not attributed to JIA

  • Physician’s global assessment of disease activity score as lowest possible on whichever scale is used

  • Duration of morning stiffness < 15 min

Definition of “clinical remission on medication (CRM)”

  • Satisfaction of the definition of clinical inactive disease for at least 6 continuous months while on therapy for JIA

Definition of “clinical remission off medication (CR)”

  • Satisfaction of the definition of clinical inactive disease for at least 12 continuous months while off all therapy for JIA

  • ACR: American College of Rheumatology; JIA: juvenile rheumatoid arthritis; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein.