Agreement between a test for high levels of anticyclic citrullinated peptide antibodies (Y) and diagnosis of RA (R) in Payet, et al1.
| R | |||
|---|---|---|---|
| + | − | ||
| Y | + | 249 | 50 |
| − | 43 | 13 | |
Sensitivity = 249/(249 + 43) = 0.85, specificity = 13/(13 + 50) = 0.21, positive predictive value = 249/(249 + 50) = 0.83, negative predictive value = 13/(13 + 43) = 0.23, positive DLR = sensitivity/(1-specificity) = 0.85/(1–0.21) = 1.07, and negative DLR = (1-sensitivity)/specificity = (1–0.85)/0.21 = 0.71. DLR: diagnostic likelihood ratios; RA: rheumatoid arthritis.