Cost of treatment with multiple courses of TNFi agents in patients with RA.
| Adalimumab, n = 204 | Etanercept, n = 290 | Infliximab, n = 69 | ||||
|---|---|---|---|---|---|---|
| n | Mean (95% CI) | n | Mean (95% CI) | n | Mean (95% CI) | |
| First course | ||||||
| Annual cost of drug* | 204 | $12.9 (12.4, 13.3) | 290 | $13.2 (12.9, 13.5) | 69 | $15.3 (13.2, 17.5) |
| Annual drug + administration costs** | 204 | $13.1 (12.6, 13.6) | 290 | $13.5 (13.2, 13.8) | 69 | $16.9 (14.6, 19.2) |
| Second course | ||||||
| Duration, mos | 159 | 16.4 (13.7, 19.1) | 105 | 15.8 (12.7, 18.9) | 37 | 21.6 (13.8, 29.4) |
| Annual cost of drug* | 159 | $13.1 (12.5, 13.8) | 105 | $11.7 (11.1, 12.2) | 37 | $18.0 (12.4, 23.5) |
| Annual drug + administration costs** | 159 | $13.8 (13.1, 14.5) | 105 | $12.4 (11.9, 13.0) | 37 | $19.7 (13.8, 25.5) |
| Total of all courses | ||||||
| Duration, mos | 204 | 37.6 (34.2, 41.1) | 290 | 39.5 (36.3, 42.8) | 69 | 41.4 (34.1, 48.7) |
| Annual cost of drug | 204 | $12.6 (12.2, 13.0) | 290 | $12.9 (12.7, 13.2) | 69 | $14.0 (12.6, 15.3) |
| Annual drug + administration costs** | 204 | $13.0 (12.5, 13.4) | 290 | $13.3 (13.0, 13.6) | 69 | $15.2 (13.8, 16.7) |
| Total cost of drug* | 204 | $39.5 (35.2, 43.8) | 290 | $41.1 (37.5, 44.7) | 69 | $44.3 (35.7, 52.9) |
| Total drug + administration costs** | 204 | $40.7 (36.3, 45.1) | 290 | $42.4 (38.7, 46.1) | 69 | $47.8 (38.7, 56.9) |