Prior | Outcome | Agents, no., name | AZA | MMF | Prednisone Alone | Tacrolimus |
---|---|---|---|---|---|---|
Flat | Serum creatinine | 3 CYC | 1.70 (0.51, 6.87) | 2.16 (0.38, 13.36) | ||
MMF | 1.25 (0.13, 10.51) | |||||
Flat | Proteinuria | 4 CYC | 0.33 (0.01, 8.06) | 1.50 (0.73, 3.64) | 0.37 (0.02, 4.36) | |
AZA | 4.59 (0.18, 145.22) | 1.09 (0.15, 7.90) | ||||
MMF | 0.24 (0.01, 3.04) | |||||
Flat | Proteinuria | 5 CYC | 0.31 (0.02, 3.60) | 1.46 (0.81, 3.04) | 0.34 (0.05, 1.90) | 1.96 (0.80, 5.11) |
AZA | 4.76 (0.38, 75.76) | 1.09 (0.18, 6.91) | 6.34 (0.53, 92.51) | |||
MMF | 0.23 (0.03, 1.38) | 1.34 (0.43, 3.90) | ||||
Pred | 5.69 (1.03, 41.32) | |||||
Sceptical | Serum creatinine | 3 CYC | 1.01 (0.60, 1.63) | 1.30 (0.68, 2.34) | ||
MMF | 1.30 (0.57, 2.73) | |||||
Sceptical | Proteinuria | 5 CYC | 0.97 (0.52, 1.78) | 0.91 (0.62, 1.38) | 0.92 (0.55, 1.56) | 0.98 (0.61, 1.58) |
AZA | 0.94 (0.46, 1.97) | 0.95 (0.46, 1.94) | 1.01 (0.47, 2.17) | |||
MMF | 1.01 (0.52, 1.94) | 1.08 (0.57, 1.96) | ||||
Pred | 1.07 (0.55, 2.04) |
Agent in columns is the numerator; agent in rows is the denominator. Outcome: serum creatinine < 132 ยตmol/l; or proteinuria < 0.5 g/day. Model convergence: empirical measures for chain convergence were excellent; Gelman-Rubin statistic R = 1.00 for each node consistently. The model converged. MMF: mycophenolate mofetil; Pred: prednisone alone; CYC: cyclophosphamide; Tac: tacrolimus; AZA: azathioprine