Table 1.

Variables associated with pneumonia with p < 0.2 in bivariate analysis.

No Pneumonia, n = 196 (%)≥ 1 Pneumoniaa, n = 30 (%)OR (95% CI)p
Cutaneous ulcers, n (%)7 (4)6 (20)6.7 (2.1–21)< 0.001
Hospitalization for non-pneumonia infections, n (%)43 (22)11 (37)2 (0.9–4.6)0.087
Major organ involvement, n (%)101 (52)18 (60)1.4 (0.6–3)0.18
Vasculitis, n (%)27 (14)10 (33)3 (1.3–7.2)0.008
SLE pneumonitis9 (5)4 (13.3)3.2 (0.9–11)0.077
No. SLE criteria, mean ± SD5.8 ± 1.56.7 ± 1.51.1–1.80.005
Weighted SDI, mean ± SD3.1 ± 54.2 ± 4.31.04 (0.1–1.1)0.044
Katz Severity Index, mean ± SD3.4 ± 2.24.3 ± 1.21.2 (1–1.4)0.016
Katz Severity Index ≥ 3, n (%)100 (51)24 (80)3.8 (1.5–9.8)0.003
Hospitalization for SLE, n (%)123 (63)29 (97)17 (2.4–130)< 0.001
Alcohol, n (%)8 (4)3 (10)2.6 (0.6–10.3)0.17
Chronic obstructive pulmonary disease, n (%)02 (6)0.017
Death from SLE, n (%)9 (5)4 (13)3.2 (0.9–11.1)0.077
Immunosuppressants use at any time, n (%)79 (40)23 (60)2.2 (1–4.9)0.049
Cyclophosphamide use at any time, n (%)57 (29)13 (43)1.9 (0.85–4)0.116
Corticosteroids (high doses), n (%)47 (24)11 (39)2 (0.9–4.6)0.087
FCGR2A HH genotype (n = 158), n (%)24 (16)10 (33.3)2.9 (1.09–7.68)0.03
  • a Pneumonia without immunosuppressant use at the time of the event. SLE: systemic lupus erythematosus; SDI: Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index.