Table 4.

Factors associated with infection and statistical significance in patients with systemic lupus erythematosus (SLE) who have diffuse alveolar hemorrhage.

CharacteristicInfected, n = 22Uninfected, n = 35p
Women, n (%)21 (95.5)28 (80.0)0.134†
JSLE, n (%)3 (13.6)11 (31.4)0.129
Treatment-naive, n (%)4 (18.1)16 (45.7)0.034
Mechanical ventilation, n (%)21 (95.5)22 (62.9)0.005
Fever, n (%)14 (63.6)17 (48.6)0.266
Hypocomplementemia, n (%)20 (90.9)19 (54.3)0.004
SLEDAI *15.5 (8–20)14 (9–18)0.0249
WBC/mm3*8.3 (4.9–12.6)8.1 (5.8–14.0)0.1586
CRP*16.4 (5.6–24.3)4.15 (0.9–16.4)0.0532

  • ↵* Results written as median (percentiles 25%–75%).

  • ↵† Fisher’s exact test, otherwise chi-square. WBC: white blood cells; CRP: C-reactive protein; JSLE: juvenile SLE; SLEDAI: Systemic Lupus Erythematosus Disease Activity Index.