Table 1.

Association analysis of 4 common variants of cGKII/PRKG2 gene in gout patients and controls.

GenotypesAllele Frequency ModelDominant Model**Recessive Model***
CaseControlMAF
A1*A2*A1/A1A1/A2A2/A2A1/A1A1/A2A2/A2CaseControlpOR (95% CI)pOR (95% CI)pOR (95% CI)
rs11736177AC2093691503696062930.460.470.520.96 (0.84–1.09)0.851.02 (0.83–1.25)0.200.86 (0.69–1.08)
rs10033237AG303346855355531740.350.360.730.98 (0.85–1.12)0.631.05 (0.87–1.26)0.160.82 (0.62–1.08)
rs7688672GA2083691533575932910.460.470.500.96 (0.84–1.09)0.901.01 (0.83–1.24)0.200.87 (0.69–1.08)
rs6837293CT2053661543725912860.460.470.961.00 (0.88–1.14)0.481.08 (0.88–1.32)0.390.91 (0.73–1.13)
  • * The major allele is referred to as A1 and the minor allele as A2.

  • ** Dominant model indicates genotype A1/A1 versus A1/A2 or A2/A2.

  • *** Recessive model indicates genotype A1/A1 or A1/A2 versus genotype A2/A2. MAF: minor allele frequency.