Associations between changes in health-related quality of life, fatigue, and productivity and changes in DAS28-CRP score from baseline to weeks 12, 16, and 24 among all randomized patients.
| Change from Baseline in: | Change from Baseline in DAS28-CRP Score | ||
|---|---|---|---|
| Week 12 | Week 16 | Week 24 | |
| SF-36 PCS score | n = 592, ρ = −0.491 | n = 592, ρ = −0.502 | n = 592, ρ = −0.548 |
| SF-36 MCS score | n = 592, ρ = −0.280 | n = 592, ρ = −0.385 | n = 592, ρ = −0.380 |
| EQ-5D score | n = 575, ρ = −0.280 | n = 575, ρ = −0.347 | n = 564, ρ = −0.254 |
| FACIT-Fatigue score | n = 582, ρ = −0.407 | n = 582, ρ = −0.481 | n = 571, ρ = −0.490 |
| Productivity score | n = 590, ρ = 0.449 | n = 590, ρ = 0.493 | n = 590, ρ = 0.521 |
All p values calculated using Spearman correlation coefficient; p < 0.0001 for all associations. DAS28-CRP: 28-joint Disease Activity Score using C-reactive protein; FACIT-Fatigue: Functional Assessment of Chronic Illness Therapy-Fatigue; SF-36 PCS/MCS: Medical Outcomes Study Short Form-36 questionnaire physical/mental component summary.